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Basal intravital leukocyte rolling in mesenteric venules

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Wild type

10 animals: 10.0 leukocytes/min

P-selectin -/-

8 animals: <0.03 leukocytes/min

Adapted from: Mayadas, TN, Johnson, RC, Rayburn, H, Hynes, RO, Wagner, DD. Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice. Cell. 74:541-554. 1993

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