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All Publications

Zhu, J., Luo, B.H., Barth, P., Schonbrun, J. and Springer, T.A.
"The Structure of a Receptor with Two Association Transmembrane Domanins on the Cell Surface: Integrin αIIbβ3"
Mol. Cell  34, 234-249  (2009).    Pub#: 519  Endnote#: 18854

Luo, B.H., Karanicolas, J., Harmacek, L.D., Baker, D., and Springer, T.A.
"Rationally Designed Integrin β3 Mutants Stabilized in the High Affinity Conformation"
J. Biol. Chem.  284, 3917-3924  (2009).    Pub#: 518  Endnote#: 18544

Springer, T.A.
"Structural basis for selectin mechanochemistry."
Proc. Natl. Acad. Sci. U.S.A.  106, 91-96  (2009).    Pub#: 517  Endnote#: 18540

Waldron, T.T., and Springer, T.A.
"Transmission of Allostery through the Lectin Domain in Selectin-Mediated Cell Adhesion."
Proc. Natl. Acad. Sci. U.S.A.  106, 85-90  (2009).    Pub#: 516  Endnote#: 18539

Zhu, J., Luo, B.H., Xiao, T., Zhang, C., Nishida, N., and Springer, T.A.
"Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces."
Mol. Cell  32, 849-861.  (2008).    Pub#: 515  Endnote#: 18561

Zhang, H., Casasnovas, J.M., Jin, M., Liu, J.H., Gahmberg, C.G., Springer, T.A., and Wang, J.H.
"An unusual allosteric mobility of the C-terminal helix of a high-affinity alphaL integrin I domain variant bound to ICAM-5. "
Mol. Cell  31, 432-437.  (2008).    Pub#: 514  Endnote#: 18723

Carman, C.V., and Springer, T.A.
"Trans-cellular migration: cell-cell contacts get intimate."
Curr. Opin. Cell Biol.   20, 533-540.  (2008).    Pub#: 513  Endnote#: 18629

Mi, L.Z., Grey, M.J., Nishida, N., Walz, T., Lu, C., and Springer, T.A.
"Functional and Structural Stability of the Epidermal Growth Factor Receptor in Detergent Micelles and Phospholipid Nanodiscs."
Biochemistry   47, 10314-10323.  (2008).    Pub#: 512  Endnote#: 18568

Springer, T.A., Zhu, J., Xiao, T.
"Structural basis for distinctive recognition of fibrinogen by the platelet integrin αIIbβ3"
J. Cell Biol.  182, 791-800  (2008).    Pub#: 511  Endnote#: 18491

Morin, N. A., Oakes, P. W., Hyun, Y.-M., Lee, D., Chin, E. Y., King, M. R., Springer, T. A., Shimaoka, M., Tang, J. X., Reichner, J. S. and Kim, M.
"Non-muscle myosin heavy chain-IIA (My-H9) mediates integrin LFA-1 de-adhesion during T lymphocyte migration"
J. Exp. Med.  205: 195-205  (2008).    Pub#: 510  Endnote#: 18475

Chen, X., Kim, T. D., Carman, C. V., Mi, L., Song, G. and Springer, T. A.
"Structural plasticity in IgSF domain 4 of ICAM-1 mediates cell surface dimerization"
Proc. Natl. Acad. Sci. U.S.A.  104: 15358-15363  (2007).    Pub#: 509  Endnote#: 18264

Vorup-Jensen, T., Chi, L., Gjelstrup, L. C., Jensen, U. B., Jewett, C. A., Xie, C., Shimaoka, M., Linhardt, R. J. and Springer, T. A.
"Binding between the integrin alphaXbeta2 (CD11c/CD18) and heparin"
J. Biol. Chem.  282:30869-77  (2007).    Pub#: 508  Endnote#: 18263

Bonasio, R., Carman, C.V., Kim, E., Sage, P.T., Love, K.R., Mempel, T.R., Springer, T.A., and von Andrian, U.H.
"Specific and covalent labeling of a membrane protein with organic fluorochromes and quantume dots"
Proc. Natl. Acad. Sci., U.S.A.  104: 14753-14758  (2007).    Pub#: 507  Endnote#: 18192

Zhu, J., Carman, C.V., Kim, M., Shimaoka, M., Springer, T.A., and Luo, B.H.
"Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling"
Blood  110: 2475-2483  (2007).    Pub#: 506  Endnote#: 18194

Vorup-Jensen, T., Waldron, T. T., Astrof, N., Shimaoka, M., Springer, T. A.
"The connection between metal ion affinity and ligand affinity in integrin I domains"
Biochim. Biophys. Acta  1774: 1148-1155  (2007).    Pub#: 505  Endnote#: 18164

Carman, C. V., Sage, P. T., Sciuto, T. E., de la Fuente, M. A., Geha, R. S., Ochs, H. D., Dvorak, H. F., Dvorak, A. M., Springer, T. A.
"Transcellular diapedesis is initiated by invasive podosomes."
Immunity  26: 1-14  (2007).    Pub#: 504  Endnote#: 18090

Zhu, J., Boylan, B., Luo, B.-H., Newman, P. J., Springer, T. A.
"Tests of the extension and deadbolt models of integrin activation."
J. Biol. Chem.  16: 11914-11920  (2007).    Pub#: 503  Endnote#: 18074

Luo, B.-H., Carman, C. V., Springer, T. A.
"Structural basis of integrin regulation and signaling."
Annu. Rev. Imm.  25: 619-647  (2007).    Pub#: 502  Endnote#: 17932

Nishida, N., Walz, T. and Springer, T.A.
"Structural transitions of complement component C3 and its activation products"
Proc. Natl. Acad. Sci. U.S.A.  103: 19737-19742  (2006).    Pub#: 501  Endnote#: 17977

Yang, W., Carman, C. V., Kim, M., Salas, A., Shimaoka, M., and Springer, T. A.
"A small molecule agonist of an integrin alphaLbeta2"
J. Biol. Chem.  281: 37904-37912  (2006).    Pub#: 500  Endnote#: 17967

Astrof, N. S., Salas, A., Shimaoka, M., Chen, J. F., and Springer, T. A.
"Importance of force linkage in mechanochemistry of adhesion receptors"
Biochemistry  45: 15020-15028  (2006).    Pub#: 499  Endnote#: 17931

Springer, T. A.
"Complement and the multifaceted functions of VWA and integrin I domains"
Structure  14: 1611-1616  (2006).    Pub#: 498  Endnote#: 17957

Swers, J. S., Widom, A., Phan, U., Springer, T. A., and Wittrup, K. D.
"A high affinity human antibody antagonist of P-selectin mediated rolling"
Biochem. Biophys. Res. Commun.   350: 508-513  (2006).    Pub#: 497  Endnote#: 17979

Huang, L., Shimaoka, M., Rondon, I., Roy, I., Chang, Q., Po, M., Dransfield, D. T., Ladner, R. C., Edge, A. S., Salas, A., Wood, C. R., Springer, T. A., and Cohen, E. H.
"Identification and characterization of a human monoclonal antagonistic antibody AL-57 that preferentially binds the high-affinity form of lymphocyte function-associated antigen-1"
J. Leuko. Biol.   80: 905-914  (2006).    Pub#: 496  Endnote#: 17599

Shimaoka, M., Kim, M., Cohen, E. H., Yang, W., Astrof, N., Peer, D., Salas, A., Ferrand, A., and Springer, T. A.
"AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity upregulation in lymphocytes"
Proc. Natl. Acad. Sci. U.S.A.  103: 13991-13996  (2006).    Pub#: 495  Endnote#: 17912

Nishida, N., Xie, C., Shimaoka, M., Cheng, Y., Walz, T., and Springer, T. A.
"Three distinctive ectodomain conformations and their interconversion in leukocyte beta2 integrins. "
Immunity  25: 583-594  (2006).    Pub#: 494  Endnote#: 17753

Chen, J. F., Yang, W., Kim, M., Carman, C. V., and Springer, T. A.
"Regulation of outside-in signaling by the beta2 I domain of integrin alphaLbeta2. "
Proc. Natl. Acad. Sci. U.S.A.  103: 13062-13067  (2006).    Pub#: 493  Endnote#: 17857

Phan, U. T., Waldron, T. T., and Springer, T. A.
"Remodeling of the lectin/EGF-like interface in P- and L-selectin increases adhesiveness and shear resistance under hydrodynamic force"
Nat. Imm.  7: 883-889  (2006).    Pub#: 492  Endnote#: 17620

Luo, B-H and Springer, T.A.
"Integrin structures and conformational signaling"
Curr. Opin. Cell Biol.  18: 1-8  (2006).    Pub#: 491  Endnote#: 17756

Jin, M., Song, G., Kim, Y.-S., Astrof, N., Shimaoka, M., Wittrup, D., and Springer, T. A.
"Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity"
Proc. Natl. Acad. U.S.A.  103: 5758-5763  (2006).    Pub#: 490  Endnote#: 16933

Salas, A., Shimaoka, M., Phan, U., Kim, M., and Springer, T. A.
"Transition from rolling to firm adhesion can be mimicked by extension of integrin aLb2 in an intermediate-affinity state."
J. Biol. Chem.  281: 10876-10882  (2006).    Pub#: 489  Endnote#: 17442

Song, G., Lazar, G. A., Kortemme, T., Shimaoka, M., Desjarlais, J. R., Baker, D., and Springer, T. A.
"Rational design of ICAM-1 variants for antagonizing integrin LFA-1-dependent adhesion."
J. Biol. Chem.  281: 5042-5049  (2006).    Pub#: 488  Endnote#: 17441

Zhang, F., Marcus, W. D., Goyal, N. H., Selvaraj, P., Springer, T. A., and Zhu, C.
"Two-dimensional kinetics regulation of aLb2-ICAM-1 interaction by conformational changes of the aL inserted domain."
J Biol Chem  280: 42207-42218  (2005).    Pub#: 487  Endnote#: 17369

Jimenez, D., Roda-Navarro, P., Springer, T. A., and Casasnovas, J. M.
"Contribution of N-linked glycans to the conformation and function of intercellular adhesion molecules ICAMs."
J Biol Chem  280: 5854-5861  (2005).    Pub#: 486  Endnote#: 16966

Song, G., Yang, Y., Liu, J.-h., Casasnovas, J., Shimaoka, M., Springer, T. A., and Wang,J. -h.
"An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin aLb2."
Proc Natl Acad Sci USA  102: 3366-3371  (2005).    Pub#: 485  Endnote#: 16536

Luo, B.-H., Carman, C. V., Takagi, J., and Springer, T. A.
"Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering."
Proc Natl Acad Sci USA  102: 3679-3684  (2005).    Pub#: 484  Endnote#: 16906

Vorup-Jensen T, Carman CV, Shimaoka M, Schuck P, Svitel J, Springer TA.
"Exposure of acidic residues as a danger signal for recognition of fibrinogen and other macromolecules by integrin aXb2."
Proc. Natl. Acad. Sci. U.S.A.  102: 1614-1619  (2005).    Pub#: 483  Endnote#: 16876

Lafuente, E. M., van Puijenbroek, A. A., Krause, M., Carman, C. V., Freeman, G. J., Berezovskaya, A., Constantine, E., Springer, T. A., Gertler, F. B., and Boussiotis, V. A.
"RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion."
Dev Cell  7: 585-595  (2004).    Pub#: 482  Endnote#: 17368

Jin M, Andricioaei I, Springer TA.
"Conversion between three conformational states of integrin I domains with a C-terminal pull spring studied with molecular dynamics."
Structure  12: 2137-2147  (2004).    Pub#: 481  Endnote#: 16558

Kim M, Carman CV, Yang W, Salas A, Springer TA.
"The primacy of affinity over clustering in regulation of adhesiveness of the integrin aLb2."
J Cell Biol  167: 1241-1253. Supplementary Info: S1,  (2004).    Pub#: 480  Endnote#: 16366

Carman CV, Springer TA.
"A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them."
J. Cell Biol.  167: 377-388. Supplementary Info: S1, S2  (2004).    Pub#: 479  Endnote#: 16849

Xie C, Shimaoka M, Xiao T, Schwab P, Klickstein LB, Springer TA.
"The integrin a subunit leg extends at a Ca2+dependent epitope in the thigh/genu interface upon activation."
Proc Natl Acad Sci USA  101: 15422-15427  (2004).    Pub#: 478  Endnote#: 16668

Chen JF, Takagi J, Xie C, Xiao T, Luo B-H, Springer TA.
"The relative influence of metal ion binding sites in the I-like domain and the interface with the hybrid domain on rolling and firm adhesion by integrin a4b7."
J Biol Chem  279: 55556-55561  (2004).    Pub#: 477  Endnote#: 16800

Artoni, A., Li, J., Mitchell, B., Ruan, J., Takagi, J., Springer, T. A., Coller, B. S., andFrench, D. L.
"Integrin β3 regions controlling binding of murine mAb 7E3: Implications for the mechanism of integrin αIIbβ3 activation."
Proc Natl Acad Sci USA  101: 13114-13120  (2004).    Pub#: 476  Endnote#: 16738

Xiao T, Takagi J, Wang J-h, Coller BS, Springer TA.
"Structural basis for allostery in integrins and binding of ligand-mimetic therapeutics to the platelet receptor for fibrinogen."
Nature  432: 59-67. Supplementary Info: S1, S2,  (2004).    Pub#: 475  Endnote#: 16500

Lu C, Shimaoka M, Salas A, Springer TA.
"The binding sites for competitive antagonists, allosteric antagonistic, and agonistic antibodies to the I domain of integrin LFA-1."
J. Immunol  173: 3971-3978  (2004).    Pub#: 474  Endnote#: 16613

Shimaoka M, Springer TA.
"Therapeutic antagonists and the conformational regulation of the b2 integrins."
Curr Top Med Chem  4: 1485-1495  (2004).    Pub#: 473  Endnote#: 16079

Springer TA, Wang J-h.
"The three-dimensional structure of integrins and their ligands, and conformational regulation of cell adhesion."
In Cell Surface Receptors, ed. KC Garcia. San Diego, CA: Elsevier  68: 29-63  (2004).    Pub#: 472  Endnote#: 16589

Luo B-H, Strokovich K, Walz T, Springer TA, Takagi J.
"Allosteric b1 integrin antibodies that stabilize the low affinity state by preventing the swing-out of the hybrid domain."
J Biol Chem  279: 27466-27471  (2004).    Pub#: 471  Endnote#: 16502

Yang Y, Jun C-D, Liu J-h, Zhang R-G, Jochimiak A, Springer, T.A., Wang, J-h.
"Structural basis for dimerization of ICAM-1 on the cell surface."
Mol Cell  14: 269-276  (2004).    Pub#: 470  Endnote#: 16471

Luo B-H, Springer TA, Takagi J.
"A specific interface between integrin transmembrane helices and affinity for ligand."
Pub Lib Sci  2: 776-786  (2004).    Pub#: 469  Endnote#: 16367

Salas, A., Shimaoka, M., Kogan, A. N., Harwood, C., von Andrian, U. H., and Springer, T.A.
"Rolling adhesion through an extended conformation of integrin aLb2 and relation to a I and b I-like domain interaction."
Immunity  20: 393-406  (2004).    Pub#: 468  Endnote#: 16362

Culi, J., Springer, T. A., Mann, R. S.
"Boca-dependent assembly of b-propeller/EGF modules in low-density lipoprotein receptor proteins."
Embo J  23: 1372-1380  (2004).    Pub#: 467  Endnote#: 16345

Yang, W., Shimaoka, M., Salas, A., Takagi, J., Springer, T. A.
"Inter-subunit signal transmission in integrins by a receptor-like interaction with a pull spring."
Proc Natl Acad Sci USA  101: 2906-2911  (2004).    Pub#: 466  Endnote#: 16063

Yang, W., Shimaoka, M., Chen, J. F., Springer, T.A.
"Activation of integrin b subunit I-like domains by one-turn C-terminal a-helix deletions."
Proc Natl Acad Sci USA  101: 2333-2338  (2004).    Pub#: 465  Endnote#: 16275

Luo, B-H., Takagi, J., Springer, T. A.
"Locking the b3 integrin I-like domain into high and low affinity conformations with disulfides."
J Biol Chem  279: 10215-10221  (2004).    Pub#: 464  Endnote#: 16236

Carman, C. V., Jun, C.-D., Salas, A., and Springer, T. A.
"Endothelial cells proactively form microvilli-like membrane projections upon ICAM-1 engagement of leukocyte LFA-11."
J Immunol  171: 6135-6144  (2003).    Pub#: 463  Endnote#: 16048

Chen, J. F., Salas, A., and Springer, T. A.
"Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster."
Nat Struct Biol  10: 995-1001  (2003).    Pub#: 462  Endnote#: 16047

Carman, C. V., and Springer, T. A.
"Integrin avidity regulation: Are changes in affinity and conformation underemphasized?"
Curr Opin Cell Biol  15: 547-556  (2003).    Pub#: 461  Endnote#: 16036

Shimaoka, M., Salas, A., Yang, W., Weitz-Schmidt, G., and Springer, T. A.
"Small molecule integrin antagonists that bind to the b2 subunit I-like domain and activate signals in one direction and block them in another."
Immunity  19: 391-402  (2003).    Pub#: 460  Endnote#: 15806

Takagi, J., Strokovich, K., Springer, T. A., and Walz, T.
"Structure of integrin a5b1 in complex with fibronectin."
EMBO J  22: 4607-4615  (2003).    Pub#: 459  Endnote#: 16024

Shimaoka, M., and Springer, T. A.
"Therapeutic antagonists and the conformational regulation of integrin structure and function."
Nat Rev Drug Disc  2:703-716  (2003).    Pub#: 458  Endnote#: 16023

Lehmann, J. C. U., Jablonski-Westrich, D., Haubold, U., Gutierrez-Ramos, J.-C., Springer,T.A., and Hamann, A.
"Overlapping and selective roles of endothelial ICAM-1 and ICAM-2 in lymphocyte trafficking."
J. Immunol.  171: 2588-2593  (2003).    Pub#: 457  Endnote#: 16001

Tohyama, Y., Katagiri, K., Pardi, R., Lu, C., Springer, T. A., and Kinashi, T.
"The critical cytoplasmic regions of the aL/b2 integrin in Rap1-induced adhesion and migration."
Mol Biol Cell  14: 2570-2582  (2003).    Pub#: 456  Endnote#: 15998

Takagi, J., Yang, Y., Liu, J-h., Wang, J-h., and Springer, T. A.
"Complex between nidogen and laminin fragments reveals a paradigmatic b-propeller interface."
Nature  424: 969-974 Supplementary Info: S1, S2,  (2003).    Pub#: 455  Endnote#: 15961

Kim, M., Carman, C. V., and Springer, T. A.
"Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins."
Science  301: 1720-1725 Supplementary Info: S1  (2003).    Pub#: 454  Endnote#: 15919

Luo, B-H., Springer, T. A., Takagi, J.
"High affinity ligand binding by integrins does not involve head separation."
J Biol Chem  278: 17185-17189  (2003).    Pub#: 453  Endnote#: 15826

Luo, B-H., Springer, T.A., Takagi, J.
"Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand."
Proc Natl Acad Sci USA  100: 2403-2408  (2003).    Pub#: 452  Endnote#: 15788

Vorup-Jensen, T., Shimaoka, M., Ostermeier, C., Hommel, U., and Springer, T.A.
"Structure and allosteric regulation of the aXb2 integrin I domain."
Proc Natl Acad Sci USA  100: 1873-1878  (2003).    Pub#: 451  Endnote#: 15787

Shimaoka, M., Xiao, T., Liu, J-H., Yang, Y., Dong, Y., Jun, C-D., McCormack, A., Zhang, R.,Joachimiak, A., Takagi, J., Wang, J-H., and Springer, T.A.
"Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation."
Cell  112: 99-111  (2003).    Pub#: 450  Endnote#: 15585

Springer, T. A.
"Predicted and experimental structures of integrins and b-propellers."
Curr Opin Struct Biol  12:802-813  (2002).    Pub#: 449  Endnote#: 15676

Shimaoka, M., Lu, C., Salas, A., Xiao, T., Takagi, J. and Springer, T.A.
"Stabilizing the integrin aM inserted domain in alternative conformations with a range of engineered disulfide bonds."
Proc Natl Acad Sci USA  99: 16737-16741  (2002).    Pub#: 448  Endnote#: 15631

Salas, A., Shimoaka, M., Chen, S., Carman, C. V. and Springer, T.A.
"Transition from rolling to firm adhesion is regulated by the conformation of the I domain of the integrin LFA-1."
J Bio Chem  277: 50255-50262  (2002).    Pub#: 447  Endnote#: 15599

Springer, T.A.
"Measurement of selectin tether bond lifetimes."
Biophys. J.  83: 2318-2323  (2002).    Pub#: 446  Endnote#: 15586

Hirose, J., Kawashima, H., Willis, M. S., Springer, T.A., Hasegawa, H., Yoshie, O., and Miyasaka, M.
"Chondroitin sulfate B exerts its inhibitory effect on secondary lymphoid tissue chemokine SLC by binding to the C-terminus of SLC."
Biochim Biophys Acta  1571: 219-224  (2002).    Pub#: 445  Endnote#: 15584

Takagi, J. and Springer, T. A.
"Integrin activation and structural rearrangment."
Immunol. Rev.  186: 141-163  (2002).    Pub#: 444  Endnote#: 15546

Takagi, J., Petre, B. M., Walz, T., and Springer, T. A.
"Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling."
Cell  110: 599-611  (2002).    Pub#: 443  Endnote#: 15418

Jing, H., Takagi, J., Liu, J-h., Lindgren, S., Zhang, R-G., Joachimiak, A., Wang, J-h., andSpringer, T. A.
"Archaeal surface layer proteins contain b-propeller, polycystic kidney disease, and b-helix domains, and are related to metazoan cell surface proteins."
Structure  10: 1453-1464  (2002).    Pub#: 442  Endnote#: 15543

Springer, T.A.
"Cesar Milstein, the father of modern immunology."
Nat Immunol  3: 501-503  (2002).    Pub#: 441  Endnote#: 15478

Springer, T.A.
"Cesar Milstein 1927-2002."
Science  296: 1253  (2002).    Pub#: 440  Endnote#: 15463

Shimaoka, M., Takagi, J. and Springer, T.A.
"Conformational regulation of integrin structure and function."
Annu Rev Biophys Biomol Struct  31: 485-516  (2002).    Pub#: 439  Endnote#: 15321

Galagan, J.E., Nusbaum, C., Roy, A., Endrizzi, M. G., Macdonald, P., FitzHugh, W., Calvo,S.,Engels, R., Smirnov, S., Atnoor, D., Brown, A., Allen, N., Naylor, J., Stange-Thomann, N., DeArellano, K., Johnson, R., Linton, L., McEwan, P., McKernan, K., Talamas, J., Tirrell, A., Ye, W., Zimmer, A., Barber, R. D., Cann, I., Graham, D. E., Grahame, D. A., Guss, A., Hedderich, R., Ingram-Smith, C., Kuettner, H. C., Krzycki, J. A., Leigh, J. A. , Li, W., Liu, J., Mukhopadhyay, B., Reeve, J. N., Smith, K., Springer, T. A., Umayam, L. A., White, O., White, R. H., Conway de Macario, E., Ferry, J. G., Jarrell, K. F., Jing, H., Macario, A. J., Paulsen, I., Pritchett, M., Sowers, K. R., Swanson, R. V., Zinder, S. H., Lander, E., Metcalf, W. W. and Birren, B.
"The genome of Methanosarcina acetivorans reveals extensive metabolic and physiological diversity."
Gen Res  12: 532-542  (2002).    Pub#: 438  Endnote#: 15288

Beglova, N., Blacklow, S.C., Takagi, J., and Springer, T.A.
"Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation."
Nat Struct Biol  9: 282-287  (2002).    Pub#: 437  Endnote#: 15202

Takagi, J., Debottis, D.P., Erickson, H.P., and Springer, T.A.
"The role of specificity-determining loop of the integrin b-subunit I-like domain in folding, association with the a subunit, and ligand binding."
Biochemistry  41: 4339-4347  (2002).    Pub#: 436  Endnote#: 15197

Ma, Q., Shimaoka, M., Lu, C., Jing, H., Carman, C.V. and Springer, T.A.
"Activation induced conformational changes in the I domain region of LFA-1."
J. Biol. Chem.  277: 10638-10641  (2002).    Pub#: 435  Endnote#: 15310

Chang, D.D., Hoang, B.Q., Liu, J. and Springer, T.A.
"Molecular basis for interaction between Icap1a PTB domain and b1 integrin."
J Biol Chem  277: 8140-8145  (2002).    Pub#: 434  Endnote#: 15283

Ueno, T., Hara, K., Swope Willis, M., Malin, M., Hoepken, U., Gray, D.H.D., Matsushima, K.,Lipp, M., Springer, T.A., Boyd, R.L., Yoshie, O. and Takahama, Y.
"Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymus."
Immunity  16: 205-218  (2002).    Pub#: 433  Endnote#: 15281

Kamata, T., Tieu, K.K., Springer, T.A. and Takada, Y.
"Amino acid residues in the aIIb subunit that are critical for ligand binding to integrin aIIbb3 are clustered in the b- propeller model."
J Biol Chem  276:44275-44283  (2001).    Pub#: 432  Endnote#: 15203

de Chateau, M., Chen, S., Salas, A. and Springer, T.A.
"Kinetic and mechanical basis of rolling through an integrin, and novel Ca2+dependent rolling and Mg2+dependent firm adhesion modalities for the a4b7-MAdCAM-1 interaction."
Biochemistry  40:13972-13979  (2001).    Pub#: 431  Endnote#: 14791

Takagi, J., Beglova, N., Yalamanchili, P., Blacklow, S.C. and Springer, T.A.
"Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin b subunits."
Proc Natl Acad Sci USA  98:11175-11180  (2001).    Pub#: 430  Endnote#: 15112

Manjunath, N., Shankar, P., Wan, J., Weninger, W., Crowley, M.A., Hieshima, K., Springer,T.A., Fan, X., Shen, H., Lieberman, J. and von Andrian, U.H.
"Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes."
J Clin Invest  108:871-878  (2001).    Pub#: 429  Endnote#: 15151

Smith, R.S., Fedyk, E.R., Springer, T.A., Mukaida, N., Iglewski, B.H. and Phipps, R.P.
"IL-8 production in human lung fibroblasts and epithelial cells activated by the Pseudomonas autoinducer N-3-oxododecanoyl homoserine lactone is transcriptionally regulated by NF-kB and activator protein-2."
J Immunol  167:366-374  (2001).    Pub#: 428  Endnote#: 15150

Jun, C.-D., Carman, C.V., Redick, S.D., Shimaoka, M., Erickson, H.P. and Springer, T.A.
"Ultrastructure and function of dimeric, soluble intercellular adhesion molecule-1 ICAM-1."
J Biol Chem  276:29019-29027  (2001).    Pub#: 427  Endnote#: 15086

Jeon, H., Meng, W., Takagi, J., Eck, M.J., Springer, T.A. and Blacklow, S.C.
"Implications for familial hypercholesterolemia from structure of the LDL receptor YWTD-EGF domain pair."
Nat Struc Biol  8:499-504  (2001).    Pub#: 426  Endnote#: 15024

Jun, C.-D., Shimaoka, M., Carman, C.V., Takagi, J. and Springer, T.A.
"Dimerization and the effectiveness of ICAM-1 in mediating LFA-1 dependent adhesion."
Proc Natl Acad Sci USA  98:6830-6835  (2001).    Pub#: 425  Endnote#: 15121

Shimaoka, M., Lu, C., Palframan, R., von Andrian, U.H., Takagi, J. and Springer, T.A.
"Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin aL I domains with high affinity and antagonist activity in vivo."
Proc Natl Acad Sci USA  98:6009-6014  (2001).    Pub#: 424  Endnote#: 14973

Takagi, J., Erickson, H.P. and Springer, T.A.
"C-terminal opening mimics "inside-out" activation of integrin a5b1."
Nature Struct Biol  8:412-416  (2001).    Pub#: 423  Endnote#: 15085

Fedyk, E.R., Jones, D., Critchley, H.O.D., Phipps, R.P., Blieden, T.A. and Springer, T.A.
"Expression of stromal-derived factor-1 is decreased by IL-1 and TNF and regulates dermal wound healing."
J Immunol  166:5749-5754  (2001).    Pub#: 422  Endnote#: 15036

Lu, C., Ferzly, M., Takagi, J. and Springer, T.A.
"Epitope mapping of antibodies to the C-terminal region of the integrin b2 subunit reveals regions that become exposed upon receptor activation."
J Immunol  166:5629-5637  (2001).    Pub#: 421  Endnote#: 14995

Lu, C., Takagi, J. and Springer, T.A.
"Association of the membrane-proximal regions of the a and b subunit cytoplasmic domains constrains an integrin in the inactive state."
J Biol Chem  276:14642-14648  (2001).    Pub#: 420  Endnote#: 15054

Zang, Q. and Springer, T.A.
"Amino acid residues in the PSI domain and cysteine-rich repeats of the integrin b2 subunit that restrain activation of the integrin aXb2."
J Biol Chem  276:6922-6929  (2001).    Pub#: 419  Endnote#: 14817

Lu, C., Shimaoka, M., Zang, Q., Takagi, J. and Springer, T.A.
"Locking in alternate conformations of the integrin aLb2 I domain with disulfide bonds reveals functional relationships among integrin domains."
Proc Natl Acad Sci USA  98:2393-2398  (2001).    Pub#: 418  Endnote#: 14975

Lu, C., Shimaoka, M., Ferzly, M., Oxvig, C., Takagi, J. and Springer, T.A.
"An isolated, surface-expressed I domain of the integrin aLb2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide."
Proc Natl Acad Sci USA  98:2387-2392  (2001).    Pub#: 417  Endnote#: 14974

Chen, S. and Springer, T.A.
"Selectin receptor-ligand bonds: Formation limited by shear rate and dissociation governed by the Bell model."
Proc Natl Acad Sci USA  98: 950-955  (2001).    Pub#: 416  Endnote#: 15023

Hioe, C.E., Chien, P.C., Lu, C., Springer, T.A., Wang, X.H., Bandres, J. and Tuen, M.
"LFA-1 expression on target cells promotes human immunodeficiency virus type 1 infection and transmission."
J Virol  75:1077-1082  (2001).    Pub#: 415  Endnote#: 15083

Springer, T.A., Jing, H. and Takagi, J.
"A novel Ca2+binding b-hairpin loop better resembles integrin sequence motifs than the EF-hand."
Cell  102: 275-277  (2000).    Pub#: 414  Endnote#: 14802

Shimaoka, M., Shifman, J.M., Jing, H., Takagi, J., Mayo, S.L. and Springer, T.A.
"Computational design of an integrin I domain stabilized in the open, high affinity conformation."
Nature Struct Biol  7:674-678  (2000).    Pub#: 413  Endnote#: 14798

Zang, Q., Lu, C., Huang, C., Takagi, J. and Springer, T.A.
"The top of the I-like domain of the integrin LFA-1 b subunit contacts the a subunit b-propeller domain near b-sheet 3."
J Biol Chem  275: 22202-22212  (2000).    Pub#: 412  Endnote#: 14786

Huang, C., Zang, Q., Takagi, J. and Springer, T.A.
"Structural and functional studies with antibodies to the integrin b2 subunit: A model for the I-like domain."
J Biol Chem  275: 21514-21524  (2000).    Pub#: 411  Endnote#: 12649

Yalamanchili, P., Lu, C., Oxvig, C. and Springer, T.A.
"Folding and function of I-domain deleted Mac-1 and LFA-1."
J Biol Chem  275:21877-21882  (2000).    Pub#: 410  Endnote#: 14779

Dustin, M.L. and Springer, T.A.
"Intercellular adhesion molecules ICAMs."
In Guidebook to the Extracellular Matrix and Adhesion Proteins. T. Kreis and R. Vale, editors. Sambrook and Tooze, New York    (1999).    Pub#: 409  Endnote#: 13747

Dustin, M.L. and Springer, T.A.
"CD2/LFA-3 CD2: T11, E rosette receptor; LFA-3: CD58."
In Guidebook to the Extracellular Matrix and Adhesion Proteins. T. Kreis and R. Vale, editors. Sambrook and Tooze, New York    (1999).    Pub#: 408  Endnote#: 13746

Dustin, M.L. and Springer, T.A.
"Lymphocyte function associated-1 LFA-1, CD11a/CD18."
In Guidebook to the Extracellular Matrix and Adhesion Proteins,. T. Kreis and R. Vale, editors. Sambrook and Tooze, New York    (1999).    Pub#: 407  Endnote#: 13745

Green, N., Rosebrook, J., Cochran, N., Tan, K., Wang, J.-h., Springer, T. A., and Briskin,M.J.
"Mutational analysis of MAdCAM-1/a4b7 interactions reveals significant binding interfaces in the second IG like domain."
Cell Adhes Comm  7: 167-181  (1999).    Pub#: 406  Endnote#: 14713

Fedyk, E. R., Ryan, D. H., Ritterman, I., and Springer, T. A.
"Maturation decreases responsiveness of human bone marrow B lineage cells to stromal-derived factor 1 SDF-1."
J Leukoc Biol  66: 667-673  (1999).    Pub#: 405  Endnote#: 14699

Bork, P., Doerks, T., Springer, T. A., and Snel, B.
"Domains in plexins: Links to integrins and transcription factors."
Trends Biochem Sci  24: 261-263  (1999).    Pub#: 404  Endnote#: 14513

Springer, T.A.
"Immunoaffinity chromatography."
In Current Protocols in Protein Science. J. E. Coligan, B. M. Dunn, H. L. Ploegh, D. W. Speicher and P. T. Wingfield, editors. John Wiley and Sons, Inc., New York Published in 1995  9.5.1-9.5.11  (1999).    Pub#: 403  Endnote#: 14618

Ma, Q., Jones, D. and Springer, T.A.
"The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment."
Immunity  10:463-471  (1999).    Pub#: 402  Endnote#: 14517

Casasnovas, J., Pieroni, C. and Springer, T.A.
"Lymphocyte function-associated antigen-1 binding residues in intercellular adhesion molecule-2 ICAM-2 and the integrin binding surface in the ICAM subfamily."
Proc Natl Acad Sci USA  96:3017-3022  (1999).    Pub#: 401  Endnote#: 14362

Oxvig, C., Lu, C. and Springer, T.A.
"Conformational changes in tertiary structure near the ligand binding site of an integrin I domain."
Proc Natl Acad Sci USA  96:2215-2220  (1999).    Pub#: 400  Endnote#: 14360

Gerwin, N., Gonzalo, J.A., Lloyd, C., Coyle, A.J., Reiss, Y., Banu, N., Wang, B., Xu, H.,Avraham, H., Engelhardt, B., Springer, T.A. and Gutierrez-Ramos, J.C.
"Prolonged eosinophil accumulation in allergic lung interstitium of ICAM-2 deficient mice results in extended hyperresponsiveness."
Immunity  10:9-19  (1999).    Pub#: 399  Endnote#: 14059

Springer, T.A.
"An extracellular b-propeller module predicted in lipoprotein and scavenger receptors, tyrosine kinases, epidermal growth factor precursor, and extracellular matrix components."
J Mol Biol  283:837-862  (1998).    Pub#: 398  Endnote#: 14115

Issekutz, A.C., Rowter, D. and Springer, T.A.
"Role of ICAM-1 and ICAM-2 and alternate CD11/CD18 ligands in neutrophil transendothelial migration."
J Leukoc Biol  65:117-126  (1999).    Pub#: 397  Endnote#: 14358

Chen, S. and Springer, T.A.
"An automatic braking system that stabilizes leukocyte rolling by an increase in selectin bond number with shear."
J Cell Biol  144:185-200  (1999).    Pub#: 396  Endnote#: 14136

Weber, C. and Springer, T.A.
"Interaction of very late antigen-4 with VCAM-1 supports transendothelial chemotaxis of monocytes by facilitating lateral migration."
J Immunol  161:6825-6834  (1998).    Pub#: 395  Endnote#: 14116

Nagashima, M., Shin'oka, T., Nollert, G., Shum-Tim, D., Hickey, P.R., Kirchhoff, A., Springer, T.A., Burke, P.R. and Mayer, J.E., Jr.
"Effects of a monoclonal antibody to P-selectin on recovery of neonatal lamb hearts after cold cardioplegic ischemia."
Circulation  98:II-391-II-398  (1998).    Pub#: 394  Endnote#: 14060

Alon, R., Chen, S., Fuhlbrigge, R., Puri, K.D. and Springer, T.A.
"The kinetics and shear threshold of transient and rolling interactions of L-selectin with its ligand on leukocytes."
Proc Natl Acad Sci USA  95:11631-11636  (1998).    Pub#: 393  Endnote#: 14135

Aoudjit, F., Potworowski, E.F., Springer, T.A. and St-Pierre, Y.
"Protection from lymphoma cell metastasis in ICAM-1 mutant mice: A posthoming event."
J Immunol  161:2333-2338  (1998).    Pub#: 392  Endnote#: 14140

Ma, Q., Jones, D., Borghesan, P.R., Segal, R.A., Nagasawa, T., Kishimoto, T., Bronson, R.T.and Springer, T.A.
"Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice."
Proc Natl Acad Sci USA  95:9448-9453  (1998).    Pub#: 391  Endnote#: 14097

Wang, J.-h. and Springer, T.A.
"Structural specializations of immunoglobulin superfamily members for adhesion to integrins and viruses."
Immunol Rev  163:197-215  (1998).    Pub#: 390  Endnote#: 13788

Tan, K., Casasnovas, J.M., Liu, J.-h., Briskin, M.J., Springer, T.A. and Wang, J.-h.
"The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition."
Structure  6:793-801  (1998).    Pub#: 389  Endnote#: 13626

Lu, C., Oxvig, C. and Springer, T.A.
"The structure of the b-propeller domain and C-terminal region of the integrin aM subunit."
J Biol Chem  273:15138-15147  (1998).    Pub#: 388  Endnote#: 14083

Petruzzelli, L., Maduzia, L. and Springer, T.A.
"Differential requirements for LFA-1 binding to ICAM-1 and LFA-1-mediated cell aggregation."
J Immunol  160:4208-4216  (1998).    Pub#: 387  Endnote#: 13075

Casasnovas, J.M., Bickford, J.K. and Springer, T.A.
"The domain structure of ICAM-1 and the kinetics of binding to rhinovirus."
J Virol  72:6244-6246  (1998).    Pub#: 386  Endnote#: 13616

Kitayama, J., Mackay, C.R., Ponath, P.D. and Springer, T.A.
"The C-C chemokine receptor CCR3 participates in stimulation of eosinophil arrest on inflammatory endothelium in shear flow."
J Clin Invest  101:2017-2024  (1998).    Pub#: 385  Endnote#: 14065

Puri, K.D., Chen, S. and Springer, T.A.
"Modifying the mechanical property and shear threshold of L-selectin adhesion independently of equilibrium properties."
Nature  392:930-933  (1998).    Pub#: 384  Endnote#: 13659

Wang, C.Y., Naka, Y., Liao, H., Oz, M.C., Springer, T.A., Gutierrez-Ramos, J.-C. and Pinsky,D.J.
"Cardiac graft intercellular adhesion molecule-1 ICAM-1 and interleukin-1 expression mediate primary isograft failure and induction of ICAM-1 in organs remote from the site of transplantation."
Circulation Research  82:762-772  (1998).    Pub#: 383  Endnote#: 13928

Oxvig, C. and Springer, T.A.
"Experimental support for a b-propeller domain in integrin a-subunits and a calcium binding site on its lower surface."
Proc Natl Acad Sci USA  95:4870-4875  (1998).    Pub#: 382  Endnote#: 13717

Casasnovas, J.M., Stehle, T., Liu, J.-h., Wang, J.-h. and Springer, T.A.
"A dimeric crystal structure for the N-terminal two domains of ICAM-1."
Proc Natl Acad Sci USA  95:4134-4139  (1998).    Pub#: 381  Endnote#: 13707

Piali, L., Weber, C., LaRosa, G., Mackay, C.R., Springer, T.A., Clark-Lewis, I. and Moser,B.
"The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig."
Eur J Immunol  28:961-972  (1998).    Pub#: 380  Endnote#: 14131

Bleul, C.C., Schultze, J.L. and Springer, T.A.
"B lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagement."
J Exp Med  187:753-762  (1998).    Pub#: 379  Endnote#: 13766

Parolin, C., Borsetti, A., Choe, H., Farzan, M., Kolchinsky, P., Heesen, M., Ma, Q., Gerard,C., Palu, G., Dorf, M.E., Springer, T. and Sodroski, J.
"Use of murine CXCR-4 as a second receptor by some T-cell-tropic human immunodeficiency viruses."
J Virol  72:1652-1656  (1998).    Pub#: 378  Endnote#: 14132

Clark, R.A., Fuhlbrigge, R.C. and Springer, T.A.
"L-selectin ligands that are O-glycoprotease-resistant and distinct from MECA-79 antigen are sufficient for tethering and rolling of lymphocytes on human high endothelial venules."
J Cell Biol  140:721-731  (1998).    Pub#: 377  Endnote#: 13689

Roth, S.J., Diacovo, T.G., Brenner, M.B., Rosat, J.-P., Buccola, J., Morita, C.T. and Springer, T.A.
"Transendothelial chemotaxis of human a/b and a/d T lymphocytes to chemokines. Eur."
J Immunol  28:104-113  (1998).    Pub#: 376  Endnote#: 13736

Pujades, C., Yauch, R., Alon, R., Masumoto, A., Burkly, L., Springer, T.A., Chen, C., Lobb,R.R. and Hemler, M.E.
"Defining extracellular integrin a chain sites that affect cell adhesion and adhesion strengthening without altering soluble ligand binding."
Mol Biol Cell  8:2647-2657  (1997).    Pub#: 375  Endnote#: 11549

Weber, C. and Springer, T.A.
"Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to aIIbb3 and stimulated by platelet-activating factor."
J Clin Invest  100:2085-2093  (1997).    Pub#: 374  Endnote#: 13578

Weber, C., Lu, C.-F., Casasnovas, J.M. and Springer, T.A.
"Role of aLb2 integrin avidity in transendothelial chemotaxis of mononuclear cells."
J Immunol  159:3968-3975  (1997).    Pub#: 373  Endnote#: 13535

Kitayama, J., Fuhlbrigge, R.C., Puri, K.D. and Springer, T.A.
"P-selectin, L-selectin, and a4 integrin have distinct roles in eosinophil tethering and arrest on vascular endothelial cells under physiological flow conditions."
J Immunol  159:3929-3939  (1997).    Pub#: 372  Endnote#: 13534

Kitayama, J., Hancock, W.W. and Springer, T.A.
"CDw145 workshop panel report."
In Leucocyte typing VI: White cell differentiation antigens. T. Kishimoto, H. Kikutani, A. E. G. K. v. d. Borne, S. M. Goyert, D. Mason, M. Miyasaka, L. Moretta, K. Okumura, S. Shaw, T. Springer, K. Sugamura and H.Zola, eds. Garland Pub., New York  754-755  (1997).    Pub#: 371  Endnote#: 13382

Kitayama, J., Ryan, M., Clark, R. and Springer, T.A.
"Endothelial cell blind panel: Flow cytometric analysis report."
In Leucocyte typing VI: White cell differentiation antigens. T. Kishimoto, H. Kikutani, A. E. G. K. v. d. Borne, S. M. Goyert, D. Mason, M. Miyasaka, L. Moretta, K. Okumura, S. Shaw,T. Springer, K. SugamuraandH. Zola, eds. Garland Pub., New York  725-733  (1997).    Pub#: 370  Endnote#: 13381

Kitayama, J. and Springer, T.A.
"Endothelial cell blind panel: Biochemical analysis report."
In Leucocyte typing VI: White cell differentiation antigens. T. Kishimoto, H. Kikutani, A. E. G. K. v. d. Borne, S. M. Goyert, D. Mason, M. Miyasaka, L. Moretta, K. Okumura, S. Shaw andT. Springer, editors. Garland Pub.,New York.  721-724  (1997).    Pub#: 369  Endnote#: 13380

Kitayama, J. and Springer, T.A.
"Endothelial cell blind panel analysis: Overview and summary."
In Leucocyte typing VI: White cell differentiation antigens. T. Kishimoto, H. Kikutani, A. E. G. K. v. d. Borne, S. M. Goyert, D. Mason, M. Miyasaka, L. Moretta, K. Okumura,S. Shaw, T. Springer, K. Sugamura and H. Zola, eds. Garland Pub., New York an  717-721  (1997).    Pub#: 368  Endnote#: 18857

Springer, T.A. and Kitayama, J.
"Endothelial cell antigens: Section report."
In Leucocyte typing VI: White cell differentiation antigens. T. Kishimoto, H. Kikutani, A. E. G. K. v. d. Borne, S. M. Goyert, D. Mason, M. Miyasaka, L. Moretta, K. Okumura, S. Shaw, T. Springer, K. Sugamuraand H. Zola,eds. Garland Pub., New York and  693-702  (1997).    Pub#: 367  Endnote#: 13378

Alon, R., Chen, S., Puri, K.D., Finger, E.B. and Springer, T.A.
"The kinetics of L-selectin tethers and the mechanics of selectin-mediated rolling."
J Cell Biol  138:1169-1180  (1997).    Pub#: 366  Endnote#: 11498

Tanabe, S., Heesen, M., Yoshizawa, I., Berman, M.A., Luo, Y., Bleul, C.C., Springer, T.A.,Okuda, K., Gerard, N. and Dorf, M.E.
"Functional expression of the CXC-chemokine receptor-4/fusin on mouse microglial cells and astrocytes."
J Immunol  159:905-911  (1997).    Pub#: 365  Endnote#: 13166

Lu, C. and Springer, T.A.
"The a subunit cytoplasmic domain regulates the assembly and adhesiveness of integrin lymphocyte function-associated antigen-1 LFA-1."
J Immunol  159:268-278  (1997).    Pub#: 364  Endnote#: 12589

Casasnovas, J.M., Springer, T.A., Liu, J.-h., Harrison, S.C. and Wang, J.-h.
"The crystal structure of ICAM-2 reveals a distinctive integrin recognition surface."
Nature  387:312-315  (1997).    Pub#: 363  Endnote#: 12860

Clark, R.A., Erickson, H.P. and Springer, T.A.
"Tenascin supports lymphocyte rolling."
J Cell Biol  137:755-765  (1997).    Pub#: 362  Endnote#: 13026

Chen, S., Alon, R., Fuhlbrigge, R.C. and Springer, T.A.
"Rolling and transient tethering of leukocytes on antibodies reveal specializations of selectins."
Proc Natl Acad Sci USA  94:3172-3177  (1997).    Pub#: 361  Endnote#: 13042

Huang, C. and Springer, T.A.
"Folding of the b-propeller domain of the integrin aL subunit is independent of the I domain and dependent on the b2 subunit."
Proc Natl Acad Sci USA  94:3162-3167  (1997).    Pub#: 360  Endnote#: 12751

Huang, C., Lu, C. and Springer, T.A.
"Folding of the conserved domain but not of flanking regions in the integrin b2 subunit requires association with the a subunit."
Proc Natl Acad Sci USA  94:3156-3161  (1997).    Pub#: 359  Endnote#: 12750

Bleul, C.C., Wu, L., Hoxie, J.A., Springer, T.A. and Mackay, C.R.
"The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes."
Proc Natl Acad Sci USA  94:1925-1930  (1997).    Pub#: 358  Endnote#: 12977

Kitayama, J., Carr, M.W., Roth, S.J., Buccola, J. and Springer, T.A.
"Contrasting responses to multiple chemotactic stimuli in transendothelial migration: heterologous desensitization in neutrophils and augmentation of migration in eosinophils."
J Immunol  158:2340-2349  (1997).    Pub#: 357  Endnote#: 12978

Aiuti, A., Webb, I.J., Bleul, C., Springer, T.A. and Gutierrez-Ramos, J.C.
"The chemokine SDF-1 is a chemoattractant for human CD34 hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34 progenitors to peripheral blood."
J Exp Med  185:111-120  (1997).    Pub#: 356  Endnote#: 12267

Puri, K.D., Finger, E.B. and Springer, T.A.
"The faster kinetics of L-selectin than of E-selectin and P-selectin rolling at comparable binding strength."
J Immunol  158:405-413  (1997).    Pub#: 355  Endnote#: 11774

Weber, K.S.C., York, M.R., Springer, T.A. and Klickstein, L.B.
"Characterization of lymphocyte function-associated antigen 1 LFA-1-deficient T cell lines: The aL and b2 subunits are interdependent for cell surface expression."
J Immunol  158:273-279  (1997).    Pub#: 354  Endnote#: 12319

Springer, T.A.
"Folding of the N-terminal, ligand-binding region of integrin a-subunits into a b-propeller domain."
Proc Natl Acad Sci USA  94:65-72  (1997).    Pub#: 353  Endnote#: 12683

Nagasawa, T., Nakajima, T., Tachibana, K., Iizasa, H., Bleul, C.C., Yoshie, O., Matsushima,K., Yoshida, N., Springer, T.A. and Kishimoto, T.
"Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin."
Proc Natl Acad Sci USA  93:14726-14729  (1996).    Pub#: 352  Endnote#: 12779

Finger, E.B., Bruehl, R.E., Bainton, D.F. and Springer, T.A.
"A differential role for cell shape in neutrophil tethering and rolling on endothelial selectins under flow."
J Immunol  157:5085-5096  (1996).    Pub#: 351  Endnote#: 12590

Fuhlbrigge, R.C., Alon, R., Puri, K.D., Lowe, J.B. and Springer, T.A.
"Sialylated, fucosylated ligands for L-selectin expressed on leukocytes mediate tethering and rolling adhesions in physiologic flow conditions."
J Cell Biol  135:837-848  (1996).    Pub#: 350  Endnote#: 11718

Alon, R., Fuhlbrigge, R.C., Finger, E.B. and Springer, T.A.
"Interactions through L-selectin between leukocytes and adherent leukocytes nucleate rolling adhesions on selectins and VCAM-1 in shear flow."
J Cell Biol  135:849-865  (1996).    Pub#: 349  Endnote#: 12103

Weber, C., Kitayama, J. and Springer, T.A.
"Differential regulation of b1- and b2-integrin avidity by chemoattractants in eosinophils."
Proc Natl Acad Sci USA  93:10939-10944  (1996).    Pub#: 348  Endnote#: 1262

Klickstein, L.B., York, M.B., de Fougerolles, A.R. and Springer, T.A.
"Localization of the binding site on intercellular adhesion molecule-3 ICAM-3 for lymphocyte function-associated antigen-1 LFA-1."
J Biol Chem  271:23920-23927  (1996).    Pub#: 347  Endnote#: 12235

Bleul, C.C., Fuhlbrigge, R.C., Casasnovas, J.M., Aiuti, A. and Springer, T.A.
"A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 SDF-1."
J Exp Med  184:1101-1110  (1996).    Pub#: 346  Endnote#: 12233

Weber, C., Alon, R., Moser, B. and Springer, T.A.
"Sequential regulation of a4b1 and a5b1 integrin avidity by CC chemokines in monocytes: Implications for transendothelial chemotaxis."
J Cell Biol  134:1063-1073  (1996).    Pub#: 345  Endnote#: 12234

Clark, R.A., Alon, R. and Springer, T.A.
"CD44 and hyaluronan-dependent rolling interactions of lymphocytes on tonsillar stroma."
J Cell Biol  134:1075-1087  (1996).    Pub#: 344  Endnote#: 12232

Bleul, C.C., Farzan, M., Choe, H., Parolin, C., Clark-Lewis, I., Sodroski, J. and Springer,T.A.
"The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry."
Nature  382:829-833  (1996).    Pub#: 343  Endnote#: 12400

Verdrengh, M., Springer, T.A., Gutierrez-Ramos, J.-C. and Tarkowski, A.
"Role of intercellular adhesion molecule 1 in pathogenesis of staphylococcal arthritis and in host defense against staphylococcal bacteremia."
Infect Immun  64:2804-2807  (1996).    Pub#: 342  Endnote#: 12901

Bruehl, R.E., Springer, T.A. and Bainton, D.F.
"Quantitation of L-selectin distribution on human leukocyte microvilli by immunogold labeling and electron microscopy."
J Histochem Cytochem  44:835-844  (1996).    Pub#: 341  Endnote#: 11790

Parkos, C.A., Colgan, S.P., Diamond, M.S., Nusrat, A., Liang, T.W., Springer, T.A. and Madara, J.L.
"Expression and polarization of intercellular adhesion molecule-1 on intestinal epithelia: Consequences for CD11b/CD18-mediated interactions with neutrophils."
Mol Med  2:489-505  (1996).    Pub#: 340  Endnote#: 12167

Diacovo, T.G., Puri, K.D., Warnock, R.A., Springer, T.A. and von Andrian, U.H.
"Platelet-mediated lymphocyte delivery to high endothelial venules."
Science  273:252-255  (1996).    Pub#: 339  Endnote#: 11753

Diacovo, T.G., Roth, S.J., Buccola, J.M., Bainton, D.F. and Springer, T.A.
"Neutrophil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the b2-integrin CD11b/CD18."
Blood  88:146-157  (1996).    Pub#: 338  Endnote#: 12140

Xu, H., Bickford, J.K., Luther, E., Carpenito, C., Takei, F. and Springer, T.A.
"Characterization of murine intercellular adhesion molecule-2."
J Immunol  156:4909-4914  (1996).    Pub#: 337  Endnote#: 12138

Wong, D.A., Davis, E.M., LeBeau, M. and Springer, T.A.
"Cloning and chromosomal localization of a novel gene encoding a human b2-integrin a subunit."
Gene  171:291-294  (1996).    Pub#: 336  Endnote#: 11604

Soriano, S.G., Wang, Y.F., Lipton, S.A., Springer, T.A., Gutierrez-Ramos, J.-C. and Hickey,P.R.
"Intercellular adhesion molecule ICAM-1 deficient mice are resistant to cerebral ischemia-reperfusion injury."
Ann Neurol  39:618-624  (1996).    Pub#: 335  Endnote#: 11536

Puri, K.D. and Springer, T.A.
"A Schiff base with mildly oxidized carbohydrate ligands stabilizes L-selectin and not P-selectin or E-selectin rolling adhesions in shear flow."
J Biol Chem  271:5404-5413  (1996).    Pub#: 334  Endnote#: 11775

Diacovo, T., Roth, S.J., Morita, C.T., Rosat, J.-P., Brenner, M.B. and Springer, T.A.
"Interactions of human a/b and g/d T lymphocyte subsets in shear flow with E-selectin and P-selectin."
J Exp Med  183:1193-1203  (1996).    Pub#: 333  Endnote#: 11886

Girard, J.-P. and Springer, T.A.
"Modulation of endothelial cell adhesion by hevin, an acidic protein associated with high endothelial venules."
J Biol Chem  271:4511-4517  (1996).    Pub#: 332  Endnote#: 12014

Dustin, M.L., Ferguson, L.M., Chan, P.-Y., Springer, T.A. and Golan, D.E.
"Visualization of CD2 interaction with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors in a contact area."
J Cell Biol  132:465-474  (1996).    Pub#: 331  Endnote#: 12139

Kelly, K.J., Williams, W.W., Jr., Colvin, R.B., Meehan, S.M., Springer, T.A., Gutiérrez-Ramos, J.-C. and Bonventre, J.V.
"Intercellular adhesion molecule-1 deficient mice are protected against ischemic renal injury."
J Clin Invest  97:1056-1063  (1996).    Pub#: 330  Endnote#: 11550

Carr, M.W., Alon, R. and Springer, T.A.
"The C-C chemokine MCP-1 modulates the avidity of b1 but not b2 integrins on T lymphocytes."
Immunity  4:179-187  (1996).    Pub#: 329  Endnote#: 11646

Finger, E.B., Puri, K.D., Alon, R., Lawrence, M.B., von Andrian, U.H. and Springer, T.A.
"Adhesion through L-selectin requires a threshold hydrodynamic shear."
Nature  379:266-269  (1996).    Pub#: 328  Endnote#: 11888

Connolly, E.S., Jr., Winfree, C.J., Springer, T.A., Naka, Y., Liao, H., Yan, S.D., Stern,D.M., Solomon, R.A., Gutierrez-Ramos, J.-C. and Pinsky, D.J.
"Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion: Role of neutrophil adhesion in the pathogenesis of stroke."
J Clin Invest  97:209-216  (1996).    Pub#: 327  Endnote#: 11794

Roth, S. J., Carr, M. W., and Springer, T. A.
"C-C chemokines, but not the C-X-C chemokines Il-8 and IP-10, stimulate transendothelial chemotaxis of T lymphocytes."
Eur J Immunol  25: 3482-3488  (1995).    Pub#: 326  Endnote#: 11887

Roth, S. J., Carr, M. W., Rose, S. S., and Springer, T. A.
"Characterization of transendothelial chemotaxis of T lymphocytes."
J Immunol Methods  188: 97-116  (1995).    Pub#: 325  Endnote#: 10714

Springer, T. A., and Cybulsky, M. I.
"Traffic signals on endothelium for leukocytes in health, inflammation, and atherosclerosis."
In Atherosclerosis and coronary artery disease, V. Fuster, R. Ross and E. J. Topol, eds. Philadelphia: Lippincott-Raven Publishers  511-537  (1995).    Pub#: 324  Endnote#: 11211

de Fougerolles, A., and Springer, T. A.
"Ideas crystallized on immunoglobulin superfamily-integrin interactions."
Chemistry and Biology  2: 639-643  (1995).    Pub#: 323  Endnote#: 12026

Gonzalo, J. A., Martinez-A, C., Springer, T. A., and Gutierrez-Ramos, J.-C.
"ICAM-1 is required for T cell proliferation but not for anergy or apoptosis induced by Staphylococcus aureus enterotoxin B in vivo."
Int Immunol  7: 1691-1698  (1995).    Pub#: 322  Endnote#: 11898

Yokota, A., Murata, N., Saiki, O., Shimizu, M., Springer, T. A., and Kishimoto, T.
"High avidity state of leukocyte function-associated antigen-1 on rheumatoid synovial fluid T lymphocytes."
J Immunol  155: 4118-4124  (1995).    Pub#: 321  Endnote#: 1185

Puri, K. D., Finger, E. B., Gaudernack, G., and Springer, T. A.
"Sialomucin CD34 is the major L-selectin ligand in human tonsil high endothelial venules."
J Cell Biol  131: 261-270  (1995).    Pub#: 320  Endnote#: 11335

Kinashi, T., Escobedo, J. A., Williams, L. T., Takatsu, K., and Springer, T. A.
"Receptor tyrosine kinase stimulates cell-matrix adhesion by phosphatidylinositol 3 kinase and phospholipase C-g1 pathways."
Blood  86: 2086-2090  (1995).    Pub#: 319  Endnote#: 11723

Diamond, M. S., Alon, R., Parkos, C. A., Quinn, M. T., and Springer, T. A.
"Heparin is an adhesive ligand for the leukocyte integrin Mac-1 CD11b/CD18."
J Cell Biol  130: 1473-1482  (1995).    Pub#: 318  Endnote#: 11254

Girard, J.-P., and Springer, T. A.
"High endothelial venules HEVs: Specialized endothelium for lymphocyte migration."
Immunol Today  16: 449-457  (1995).    Pub#: 317  Endnote#: 11699

Huang, C., and Springer, T. A.
"A binding interface on the I domain of lymphocyte function associated antigen-1 LFA-1 required for specific interaction with intercellular adhesion molecule 1 ICAM-1."
J Biol Chem  270: 19008-19016  (1995).    Pub#: 316  Endnote#: 10864

Klickstein, L. B., York, M. R., Luther, E., and Springer, T. A.
"Identification of workshop endothelial section mAb that recognize novel glycosylphosphatidylinositol-anchored antigens."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T.Kishimoto,T. Morimoto, J. Ritz, S.Shaw, R. Silverstein,T. Springer, T. Tedder and R. Todd, eds. New York: Oxford University Press  1850-1852  (1995).    Pub#: 315  Endnote#: 11901

Girard, J.-P., and Springer, T. A.
"Expression of sialomucin CD34 by high endothelial venules HEV in human tonsils."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. M. Harlan, T. Kishimoto, C. Morimoto, J. Ritz, S.Shaw, R. L.Silverstein, T. A. Springer,T. F. Tedder andR. F. Todd, eds. New York: Oxford Universi  1801-1803  (1995).    Pub#: 314  Endnote#: 10813

Wong, D. A., and Springer, T. A.
"Integrin b7 pre-CD report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. NewYork:Oxford University Press  1669-1670  (1995).    Pub#: 313  Endnote#: 11602

Wong, D. A., and Springer, T. A.
"CD104 b4 cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. G. Boumsell, W., W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R.Todd, eds.New York: OxfordUniversityPress  1667-1668  (1995).    Pub#: 312  Endnote#: 11601

Cepek, K. L., Wong, D. A., Brenner, M. B., and Springer, T. A.
"CD103 aE cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd,eds. New York: Oxford University Press  1666-1667  (1995).    Pub#: 311  Endnote#: 11600

Wong, D. A., and Springer, T. A.
"CD61 b3 cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. New York: Oxford University Press  1664-1665  (1995).    Pub#: 310  Endnote#: 11599

Wong, D. A., and Springer, T. A.
"CD51 aV and CD51/CD61 complex cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T.Tedder andR. Todd, eds. NewYork:Oxford University Press  1663-1664  (1995).    Pub#: 309  Endnote#: 11598

Wong, D. A., and Springer, T. A.
"Adhesion structure subpanels 7 and 8, b3, b4, b7 integrins and novel functional antigens: CD51, CD61, CD103, and CD104."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T.Kishimoto,T. Morimoto, J. Ritz, S.Shaw, R. Silverstein,T. Springer, T. Tedder and R. Todd, eds. New York: Oxford University Press  1655-1659  (1995).    Pub#: 308  Endnote#: 11597

Luk, J., Luther, E., Diamond, M. S., and Springer, T. A.
"Subunit specificity and epitope mapping of Mac-1 and p150,95 mAb using chimeric CD11b x CD11c transfectants."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto,T. Morimoto, J.Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. New York: Oxford University Press  1599-1601  (1995).    Pub#: 307  Endnote#: 11596

Huang, C., and Springer, T. A.
"Domain localization and correlation with inhibition of function of workshop CD11a mAb."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz,S. Shaw, R. Silverstein, T.Springer, T. Tedder and R. Todd, eds. New York: Oxford University Press  1595-1597  (1995).    Pub#: 306  Endnote#: 11595

Petruzzelli, L., Maduzia, L., and Springer, T. A.
"Stimulation of binding of LFA-1 bearing cells to ICAM-1 and ICAM-3."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedderand R.Todd, eds. New York:Oxford University Press  1594-1595  (1995).    Pub#: 305  Endnote#: 11594

Petruzzelli, L., and Springer, T. A.
"CD18 cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds.New York:OxfordUniversityPress  1592-1593  (1995).    Pub#: 304  Endnote#: 11593

Luk, J., and Springer, T. A.
"CD11c cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. New York:Oxford UniversityPress  1590-1592  (1995).    Pub#: 303  Endnote#: 11592

Luk, J., and Springer, T. A.
"CD11b cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. New York:Oxford UniversityPress  1588-1590  (1995).    Pub#: 302  Endnote#: 11591

Petruzzelli, L., Huang, C., and Springer, T. A.
"CD11a cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, C. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. New York:Oxford UniversityPress  1586-1587  (1995).    Pub#: 301  Endnote#: 11136

Petruzzelli, L., Luk, J., and Springer, T. A.
"Adhesion structure subpanel 5, leukocyte integrins: CD11a, CD11b, CD11c, CD18."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein,T. Springer, T. Tedderand R. Todd, eds.New York: Oxford University Press  1581-1585  (1995).    Pub#: 300  Endnote#: 11590

Klickstein, L. B., de Fougerolles, A. R., York, M. R., and Springer, T. A.
"Localization of the LFA-1 binding site on ICAM-3 CD50 by epitope mapping and deletion mutagenesis."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T.Springer, T. Tedder and R. Todd, eds. New York: Oxford University Press  1563-1566  (1995).    Pub#: 299  Endnote#: 11589

de Fougerolles, A. R., and Springer, T. A.
"Characterization of the ICAM-3/LFA-1 interaction and its role in immune responses."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S.Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd,eds. New York: Oxford University Press  1557-1559  (1995).    Pub#: 298  Endnote#: 11588

Klickstein, L. B., and Springer, T. A.
"CD102 ICAM-2 cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. New York: Oxford UniversityPress  1550-1552  (1995).    Pub#: 297  Endnote#: 11587

Klickstein, L. B., and Springer, T. A.
"CD54 ICAM-1 cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. NewYork:Oxford UniversityPress  1548-1550  (1995).    Pub#: 296  Endnote#: 11586

Klickstein, L. B., and Springer, T. A.
"CD50 ICAM-3 cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. NewYork:Oxford UniversityPress  1546-1547  (1995).    Pub#: 295  Endnote#: 11585

Klickstein, L. B., and Springer, T. A.
"Adhesion structure subpanel 4: CD50 ICAM-3, CD54 ICAM-1, and CD102 ICAM-2."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R.Silverstein, T.Springer, T.TedderandR. Todd, eds. NewYork: Oxford University Press  1542-1545  (1995).    Pub#: 294  Endnote#: 11584

Diacovo, T., and Springer, T. A.
"CD62L L-selectin cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. NewYork: OxfordUniversityPress  1503-1504  (1995).    Pub#: 293  Endnote#: 11583

Diacovo, T., and Springer, T. A.
"CD62E E-selectin cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. NewYork: OxfordUniversityPress  1501-1503  (1995).    Pub#: 292  Endnote#: 11582

Diacovo, T., and Springer, T. A.
"CD62P P-selectin cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. NewYork: OxfordUniversityPress  1500-1501  (1995).    Pub#: 291  Endnote#: 11581

Diacovo, T., and Springer, T. A.
"Adhesion structure subpanel 2, selectins: CD62E, CD62L, and CD62P."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedderand R.Todd, eds. New York: Oxford University Press  1498-1499  (1995).    Pub#: 290  Endnote#: 11580

Klickstein, L. B., York, M. R., Luther, E., and Springer, T. A.
"Identification of novel GPI-anchored antigens by analysis of GPI-anchor-deficient cells with mAb in the blind panel."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T.Morimoto, J. Ritz, S. Shaw,R. Silverstein, T.Springer, T. Tedder and R. Todd, eds. New York: Oxford University Press  1478-1481  (1995).    Pub#: 289  Endnote#: 11579

Klickstein, L. B., and Springer, T. A.
"CDw108 cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. New York: Oxford University Press  1477-1478  (1995).    Pub#: 288  Endnote#: 11578

Klickstein, L. B., and Springer, T. A.
"CD59 cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds.New York:OxfordUniversityPress  1476-1477  (1995).    Pub#: 287  Endnote#: 11577

Klickstein, L. B., and Springer, T. A.
"CD58 cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds.New York:OxfordUniversityPress  1475-1476  (1995).    Pub#: 286  Endnote#: 11576

Klickstein, L. B., and Springer, T. A.
"CD55 cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds.New York:OxfordUniversityPress  1473-1474  (1995).    Pub#: 285  Endnote#: 11575

Klickstein, L. B., and Springer, T. A.
"CD48 cluster report."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds.New York:OxfordUniversityPress  1472-1473  (1995).    Pub#: 284  Endnote#: 11574

Klickstein, L. B., and Springer, T. A.
"Adhesion structure subpanel 1, E rosetting/GPI anchor: CD2, CD48, CD55, CD58, CD99 and CDw108."
In Leucocyte typing V: White cell differentiation antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, C. Morimoto,J. Ritz, S.Shaw,R. Silverstein, T.Springer, T. Tedder and R. Todd, eds. New York: Oxford University Press  1468-1471  (1995).    Pub#: 283  Endnote#: 11573

Springer, T. A., Luther, E., and Klickstein, L. B.
"Adhesion Structures: Section Report."
In Leukocyte typing V: White cell differention antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder andR. Todd, eds. NewYork: Oxford University Press  1443-1467  (1995).    Pub#: 282  Endnote#: 10673

Greaves, M. F., Titley, I., Colman, S. M., Buhring, H.-J., Campos, L., Castoldi, G. L., Garrido, F., Gaudernack, G., Girard, J.-P., Ingles-Esteve, J., Invernizzi, R., Knapp, W., Lansdorp, P. M., Lanza, F., Merle-Beral, H., Parravicini, C., Razak, K., Ruiz-Cabello, F., Springer, T. A., Van Der Schoot, C. E., and Sutherland, D. R.
"Report on the CD34 cluster workshop."
In Leucocyte typing V: white cell differentiation antigens, S. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, C. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder andR. Todd, eds. NewYork: Oxford University Press  840-846  (1995).    Pub#: 281  Endnote#: 10344

Shaw, S., Luce, G. G., Gilks, W. R., Anderson, K., Ault, K., Bochner, B. S., Boumsell, L.,Denning, S. M., Engleman, E. G., Fleisher, T., Freedman, A. S., Fox, D. A., Gailit, J., Gutierrez-Ramos, J. C., Hurtubise, P. E., Lansdorp, P., Lotze, M. T., Mawhorter, S., Marti, G., Matsuo, Y., Minowada, J., Michelson, A., Picker, L., Ritz, J., Roos, E., Van Der Schoot, C. E., Springer, T. A., Tedder, T. F., Telen, M. J., Thompson, J. S., and Valent, P.
"Leucocyte differentiation antigen database."
In Leucocyte Typing V: White Cell Differentiation Antigens, S. F. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, T. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder and R. Todd, eds. New York: OxfordUniversity Press  16-198  (1995).    Pub#: 280  Endnote#: 0

Kassner, P. D., Alon, R., Springer, T. A., and Hemler, M. E.
"Specialized functional properties of the integrin a4 cytoplasmic domain."
Mol Biol Cell  6: 661-674  (1995).    Pub#: 279  Endnote#: 11457

Petruzzelli, L., Maduzia, L., and Springer, T. A.
"Activation of LFA-1 CD11a/CD18 and Mac-1 CD11b/CD18 mimicked by an antibody directed against CD18."
J Immunol  155: 854-866  (1995).    Pub#: 278  Endnote#: 11481

Casasnovas, J. M., and Springer, T. A.
"Kinetics and thermodynamics of virus binding to receptor: Studies with rhinovirus, intercellular adhesion molecule-1 ICAM-1, and surface plasmon resonance."
J Biol Chem  270: 13216-13224  (1995).    Pub#: 277  Endnote#: 11311

Sugie, K., Nakamura, K., Teshigawara, K., Diamond, M. S., Springer, T. A., Nakamura, Y.,Leonard, W. J., Uchida, A., and Yodoi, J.
"Activation of natural killer cells by the mAb YTA-1 that recognizes leukocyte function-associated antigen-1."
Int Immunol  7: 763-769  (1995).    Pub#: 276  Endnote#: 9222

Alon, R., Feizi, T., Yuen, C.-T., Fuhlbrigge, R. C., and Springer, T. A.
"Glycolipid ligands for selectins support leukocyte tethering and rolling under physiologic flow conditions."
J Immunol  154: 5356-5366  (1995).    Pub#: 275  Endnote#: 11210

Springer, T. A.
"Signals on endothelium for lymphocyte recirculation and leukocyte emigration: The area code paradigm."
In The Harvey Lectures, Series 89, T. H. S. o. N. York, ed. New York: Wiley-Liss, Inc.  53-103  (1995).    Pub#: 274  Endnote#: 11209

Alon, R., Hammer, D. A., and Springer, T. A.
"Lifetime of the P-selectin: carbohydrate bond and its response to tensile force in hydrodynamic flow."
Nature  374: 539  (1995).    Pub#: 273  Endnote#: 13043

de Fougerolles, A. R., Diamond, M. S., and Springer, T. A.
"Heterogenous glycosylation of ICAM-3 and lack of interaction with Mac-1 and p150,95."
Eur J Immunol  25: 1008-1012  (1995).    Pub#: 272  Endnote#: 11207

Alon, R., Kassner, P. D., Carr, M. W., Finger, E. B., Hemler, M. E., and Springer, T. A.
"The integrin VLA-4 supports tethering and rolling in flow on VCAM-1."
J Cell Biol  128: 1243-1253  (1995).    Pub#: 271  Endnote#: 11028

Lawrence, M. B., Berg, E. L., Butcher, E. C., and Springer, T. A.
"Rolling of lymphocytes and neutrophils on peripheral node addressin and subsequent arrest on ICAM-1 in shear flow."
Eur J Immunol  25: 1025-1031  (1995).    Pub#: 270  Endnote#: 10753

Kinashi, T., and Springer, T. A.
"Regulation of cell-matrix adhesion by receptor tyrosine kinases."
Leuk Lymphoma  18: 203-208  (1995).    Pub#: 269  Endnote#: 10403

Springer, T. A.
"Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration."
Annu Rev Physiol  57: 827-872  (1995).    Pub#: 268  Endnote#: 10962

Girard, J.-P., and Springer, T. A.
"Cloning from purified high endothelial venule cells of hevin, a close relative of the antiadhesive extracellular matrix protein SPARC."
Immunity  2: 113-122  (1995).    Pub#: 267  Endnote#: 11112

Kinashi, T., St.Pierre, Y., and Springer, T. A.
"Expression of glycophosphatidylinositol GPI-anchored and non-anchored isoforms of vascular cell adhesion molecule 1 in murine stromal and endothelial cells."
J of Leukoc Biol  57, 168-173  (1995).    Pub#: 266  Endnote#: 9920

Alon, R., Rossiter, H., Wang, X., Springer, T. A., and Kupper, T. S.
"Distinct cell surface ligands mediate T lymphocyte attachment and rolling on P- and E-selectin under physiological flow."
J Cell Biol  127: 1485-1495  (1994).    Pub#: 265  Endnote#: 10713

Butini, L., de Fougerolles, A. R., Vaccarezza, M., Graziosi, C., Cohen, D. I., Montroni,M.,Springer, T. A., Pantaleo, G., and Fauci, A. S.
"Intercellular adhesion molecules ICAM-1 ICAM-2 and ICAM-3 function as counter-receptors for lymphocyte function-associated molecule 1 in human immunodeficiency virus-mediated syncytia formation."
Eur J Immunol  24: 2191-2195  (1994).    Pub#: 264  Endnote#: 10954

Casasnovas, J. M., Reed, R. R., and Springer, T. A.
"Kinetics of receptor and virus interaction and receptor-induced virus disruption: Methods for study with surface plasmon resonance."
Methods: A Companion to Methods in Enzymology  6: 157-167  (1994).    Pub#: 263  Endnote#: 10401

Diacovo, T. G., de Fougerolles, A. R., Bainton, D. F., and Springer, T. A.
"A functional integrin ligand on the surface of platelets: Intercellular adhesion molecule-2."
J Clin Invest  94: 1243-1251  (1994).    Pub#: 262  Endnote#: 10865

Casasnovas, J. M., and Springer, T. A.
"The pathway of rhinovirus disruption by soluble intercellular adhesion molecule 1 ICAM-1: An intermediate in which ICAM-1 is bound and RNA is released."
J Virol  68: 5882-5889  (1994).    Pub#: 261  Endnote#: 10359

Kinashi, T., and Springer, T. A.
"Adhesion molecules in hematopoietic cells."
Blood Cells  20: 25-44  (1994).    Pub#: 260  Endnote#: 11023

Borregaard, N., Kjeldsen, L., Sengelov, H., Diamond, M. S., Springer, T. A., Anderson, H.C.,Kishimoto, T. K., and Bainton, D. F.
"Changes in subcellular localization and surface expression of L-selectin, alkaline phosphatase, and Mac-1 in human neutrophils during stimulation with inflammatory mediators."
J Leukoc Biol  56: 80-87  (1994).    Pub#: 259  Endnote#: 10719

Xu, H., Gonzalo, J. A., St.Pierre, Y., Williams, I. R., Kupper, T. S., Cotran, R. S., Springer, T. A., and Gutierrez-Ramos, J.-C.
"Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice."
J Exp Med  180: 95-109  (1994).    Pub#: 258  Endnote#: 10724

Diamond, M. S., and Springer, T. A.
"The dynamic regulation of integrin adhesiveness."
Current Biology  4: 506-517  (1994).    Pub#: 257  Endnote#: 10686

Carr, M. W., Roth, S. J., Luther, E., Rose, S. S., and Springer, T. A.
"Monocyte chemoattractant protein-1 is a major T lymphocyte chemoattractant."
Proc Natl Acad Sci USA  91: 3652-3656  (1994).    Pub#: 256  Endnote#: 10271

Lawrence, M. B., Bainton, D. F., and Springer, T. A.
"Neutrophil tethering to and rolling on E-selectin are separable by requirement for L-selectin."
Immunity  1: 137-145  (1994).    Pub#: 255  Endnote#: 10404

Bilsland, C. A. G., Diamond, M. S., and Springer, T. A.
"The leukocyte integrin p150,95 CD11c/CD18 as a receptor for iC3b: Activation by a heterologous b subunit and localization of a ligand recognition site to the I domain."
J Immunol  152: 4582-4589  (1994).    Pub#: 254  Endnote#: 10077

Vonderheide, R. H., Tedder, T. F., Springer, T. A., and Staunton, D. E.
"Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4."
J Cell Biol  125: 215-222  (1994).    Pub#: 253  Endnote#: 10072

Bilsland, C. A. G., and Springer, T. A.
"Cloning and expression of the chicken CD18 cDNA."
J of Leukoc Biol  55: 501-506  (1994).    Pub#: 252  Endnote#: 10076

Kinashi, T., and Springer, T. A.
"Steel factor and c-kit regulate cell-matrix adhesion."
Blood  83: 1033-1038  (1994).    Pub#: 251  Endnote#: 9921

de Fougerolles, A. R., Qin, X., and Springer, T. A.
"Characterization of the function of ICAM-3 and comparison to ICAM-1 and ICAM-2 in immune responses."
J Exp Med  179: 619-629  (1994).    Pub#: 250  Endnote#: 10079

Springer, T. A.
"Traffic signals for lymphocyte recirculation and leukocyte emigration: The multi-step paradigm."
Cell  76: 301-314  (1994).    Pub#: 249  Endnote#: 10150

Rodríguez, C. L., Nueda, A., Grospierre, B., Sánchez-Madrid, F., Fischer, A.,Springer, T. A., and Corbí, A. L.
"Characterization of two new CD18 alleles causing severe leukocyte adhesion deficiency."
Eur J Immunol  23: 2792-2798  (1993).    Pub#: 248  Endnote#: 11208

Springer, T. A.
"Adhesion molecules in immunity and inflammation."
In Clinical aspects of immunology, P. J. Lachmann, K. Peters, F. S. Rosen and M. J. Walport, eds. Boston: Blackwell Scientific Publications  199-219  (1993).    Pub#: 247  Endnote#: 10222

Lawrence, M. B., and Springer, T. A.
"Neutrophils roll on E-selectin."
J Immunol  151: 6338-6346  (1993).    Pub#: 246  Endnote#: 9912

Sengelov, H., Kjeldsen, L., Diamond, M. S., Springer, T. A., and Borregaard, N.
"Subcellular localization and dynamics of Mac-1 aMb2 in human neutrophils."
J Clin Invest  92: 1467-1476  (1993).    Pub#: 245  Endnote#: 9739

Springer, T. A.
"Adhesion receptors in inflammation: a précis."
In Application of Basic Science to Hematopoiesis and Treatment of Disease, E. D. Thomas and S. K. Carter, eds. New York: Raven Press  231-239  (1993).    Pub#: 244  Endnote#: 8663

Juan, M., Vilella, R., Mila, J., Yagüe, J., Miralles, A., Campbell, K. S., Friedrich,R.J., Cambier, J., Vives, J., de Fougerolles, A. R., and Springer, T. A.
"CDw50 and ICAM-3: Two names for the same molecule."
Eur J Immunol  23: 1508-1512  (1993).    Pub#: 243  Endnote#: 9554

Martin, S., Martin, A., Staunton, D. E., and Springer, T. A.
"Functional studies of truncated soluble ICAM-1 expressed in E. coli."
Antimicrob Agents Chemother  37: 1278-1284  (1993).    Pub#: 242  Endnote#: 9287

Hondalus, M. K., Diamond, M. S., Springer, T. A., and Mosser, D. M.
"The intracellular bacterium rhodococcus equi uses complement receptors to bind to mammalian cells."
Infect Immun  61: 2919-2929  (1993).    Pub#: 241  Endnote#: 9115

Martin, S., Casasnovas, J. M., Staunton, D. E., and Springer, T. A.
"Efficient neutralization and disruption of rhinovirus by chimeric ICAM-1/immunoglobulin molecules."
J Virol  67: 3561-3568  (1993).    Pub#: 240  Endnote#: 9778

Kirchhausen, T., Staunton, D. E., and Springer, T. A.
"Location of the domains of ICAM-1 by immunolabeling and single-molecule electron microscopy."
J Leukoc Biol  53: 342-346  (1993).    Pub#: 239  Endnote#: 8662

de Fougerolles, A. R., Klickstein, L. B., and Springer, T. A.
"Cloning and expression of intercellular adhesion molecule 3 reveals strong homology to other immunoglobulin family counter-receptors for lymphocyte function-associated antigen-1."
J Exp Med  177: 1187-1192  (1993).    Pub#: 238  Endnote#: 9628

Diamond, M. S., Garcia-Aguilar, J., Bickford, J. K., Corbi, A. L., and Springer, T. A.
"The I domain is a major recognition site on the leukocyte integrin Mac-1 CD11b/CD18 for four distinct adhesion ligands."
J Cell Biol  120: 1031-1043  (1993).    Pub#: 237  Endnote#: 9497

Diamond, M. S., and Springer, T. A.
"A subpopulation of Mac-1 CD11b/CD18 molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen."
J Cell Biol  120: 545-556  (1993).    Pub#: 236  Endnote#: 9116

Staunton, D. E., Ockenhouse, C. F., and Springer, T. A.
"Soluble intercellular adhesion molecule-1 immunoglobulin G1 immunoadhesion mediates phagocytosis of malaria-infected erythrocytes."
J Exp Med  176: 1471-1476  (1992).    Pub#: 235  Endnote#: 9475

Xu, H., Tong, I. L., de Fougerolles, A. R., and Springer, T. A.
"Isolation, characterization, and expression of mouse ICAM-2 complementary and genomic DNA."
J Immunol  149: 2650-2655  (1992).    Pub#: 234  Endnote#: 8879

Carpen, O., Pallai, P., Staunton, D. E., and Springer, T. A.
"Association of intercellular adhesion molecule-1 ICAM-1 with actin-containing cytoskeleton and a-actinin."
J Cell Biol  118: 1223-1234  (1992).    Pub#: 233  Endnote#: 9537

Vonderheide, R. H., and Springer, T. A.
"Lymphocyte adhesion through VLA-4: Evidence for a novel binding site in the alternatively spliced domain of VCAM-1 and an additional a4 integrin counter-receptor on stimulated endothelium."
J Exp Med  175: 1433-1442  (1992).    Pub#: 232  Endnote#: 8248

Chan, P.-Y., and Springer, T. A.
"Effect of lengthening lymphocyte function-associated antigen 3 on adhesion to CD2."
Mol Biol Cell  3: 157-166  (1992).    Pub#: 231  Endnote#: 8250

Ockenhouse, C. F., Betageri, R., Springer, T. A., and Staunton, D. E.
"Plasmodium falciparum-infected erythrocytes bind ICAM-1 at a site distinct from LFA-1, Mac-1, and human rhinovirus."
Cell  68: 63-69  (1992).    Pub#: 230  Endnote#: 8246

de Fougerolles, A. R., and Springer, T. A.
"Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes."
J Exp Med  175: 185-190  (1992).    Pub#: 229  Endnote#: 8108

Dustin, M. L., Carpen, O., and Springer, T. A.
"Regulation of locomotion and cell-cell contact area by the LFA-1 and ICAM-1 adhesion receptors."
J Immunol  148: 2654-2663  (1992).    Pub#: 228  Endnote#: 6810

Tözeren, A., Sung, K.-L. P., Sung, L. A., Dustin, M. L., Chan, P.-Y., Springer, T. A.,and Chien, S.
"Micromanipulation of adhesion of a Jurkat cell to a planar bilayer membrane containing lymphocyte function-associated antigen 3 molecules."
J Cell Biol  116: 997-1006  (1992).    Pub#: 227  Endnote#: 8249

Staunton, D. E., Gaur, A., Chan, P.-Y., and Springer, T. A.
"Internalization of a major group human rhinovirus does not require cytoplasmic or transmembrane domains of ICAM-1."
J Immunol  148: 3271-3274  (1992).    Pub#: 226  Endnote#: 8247

Tözeren, A., Mackie, L. H., Lawrence, M. B., Chan, P.-Y., Dustin, M. L., and Springer,T. A.
"Micromanipulation of adhesion of phorbol 12-myristate-13-acetate-stimulated T lymphocytes to planar membranes containing intercellular adhesion molecule-1."
Biophys J  63: 247-258  (1992).    Pub#: 225  Endnote#: 7459

Mosser, D. M., Springer, T. A., and Diamond, M. S.
"Leishmania promastigotes require opsonic complement to bind to the human leukocyte integrin Mac-1 CD11b/CD18."
J Cell Biol  116: 511-520  (1992).    Pub#: 224  Endnote#: 8256

Springer, T. A.
"The next cluster of differentiation CD workshop."
Nature  354: 415-416  (1991).    Pub#: 223  Endnote#: 8566

Springer, T. A.
"Cell adhesion: A birth certificate for CD2."
Nature  353: 704-705  (1991).    Pub#: 222  Endnote#: 8433

Schwartz, M. A., Ingber, D. E., Lawrence, M., Springer, T. A., and Lechene, C.
"Multiple integrins share the ability to induce elevation of intracellular pH."
Experimental Cell Research  195: 533-535  (1991).    Pub#: 221  Endnote#: 7588

Carpen, O., Dustin, M. L., Springer, T. A., Swafford, J. A., Smith, L. A., and Caulfield,J.P.
"Motility and ultrastructure of large granular lymphocytes on lipid bilayers reconstituted with adhesion receptors LFA-1, ICAM-1 and two isoforms of LFA-3."
J Cell Biol  115: 861-871  (1991).    Pub#: 220  Endnote#: 8054

Hibbs, M. L., Jakes, S., Stacker, S. A., Wallace, R. W., and Springer, T. A.
"The cytoplasmic domain of the integrin lymphocyte function-associated antigen 1 b subunit: sites required for binding to intercellular adhesion molecule 1 and the phorbol ester-stimulated phosphorylation site."
J Exp Med  174: 1227-1238  (1991).    Pub#: 219  Endnote#: 8018

Lawrence, M. B., and Springer, T. A.
"Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins."
Cell  65: 859-873  (1991).    Pub#: 218  Endnote#: 7962

Springer, T. A., and Lasky, L. A.
"Sticky sugars for selectins."
Nature  349: 196-197  (1991).    Pub#: 217  Endnote#: 7771

Kaufman, Y., Tseng, E., and Springer, T. A.
"Cloning of the murine lymphocyte function-associated molecule-1 LFA-1 a subunit and its expression in COS cells."
J Immunol  147: 369-371  (1991).    Pub#: 216  Endnote#: 7822

Diamond, M. S., Staunton, D. E., Marlin, S. D., and Springer, T. A.
"Binding of the integrin Mac-1 CD11b/CD18 to the third Ig-like domain of ICAM-1 CD54 and its regulation by glycosylation."
Cell  65: 961-971  (1991).    Pub#: 215  Endnote#: 7813

Chan, P.-Y., Lawrence, M. B., Dustin, M. L., Ferguson, L. M., Golan, D. E., and Springer,T.A.
"Influence of receptor lateral mobility on adhesion strengthening between membranes containing LFA-3 and CD2."
J Cell Biol  115: 245-255  (1991).    Pub#: 214  Endnote#: 7764

de Fougerolles, A. R., Stacker, S. A., Schwarting, R., and Springer, T. A.
"Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1."
J Exp Med  174: 253-267  (1991).    Pub#: 213  Endnote#: 7329

Springer, T. A.
"Isolation of proteins using antibodies: Immunoaffinity chromatography and immunoprecipitation."
In Current Protocols in Immunology, J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach and W. Strober, eds. New York: Greene Publishing Associates and WileyInterscience  8.2.1-8.3.11  (1991).    Pub#: 212  Endnote#: 7267

Stacker, S. A., and Springer, T. A.
"Leukocyte integrin p150,95 CD11c/CD18 functions as an adhesion molecule binding to a counter-receptor on stimulated endothelium."
J Immunol  146: 648-655  (1991).    Pub#: 211  Endnote#: 7232

Vonderheide, R. H., and Springer, T. A.
"VLA-4-dependent adhesion of lymphocytic cell lines to cultured endothelium."
In Lymphatic Tissues and In Vivo Immune Responses, B. Imhof and e. al., eds. New York: Marcel Dekker, Inc.  873-876  (1991).    Pub#: 210  Endnote#: 7148

Dustin, M. L., and Springer, T. A.
"Role of lymphocyte adhesion receptors in transient interactions and cell locomotion."
Annu Rev Immunol  9: 27-66  (1991).    Pub#: 209  Endnote#: 7126

Hibbs, M. L., Xu, H., Stacker, S. A., and Springer, T. A.
"Regulation of adhesion to ICAM-1 by thecytoplasmic domain of LFA-1 integrin b subunit."
Science  251: 1611-1613  (1991).    Pub#: 208  Endnote#: 7121

Springer, T. A.
"Area code molecules of lymphocytes."
In Cell to Cell Interaction: a Karger Symposium, M. M. Burger, B. Sordat and R. M. Zinkernagel, eds. Basel: S. Karger AG,  16-39  (1990).    Pub#: 207  Endnote#: 7324

Diamond, M. S., Staunton, D. E., de Fougerolles, A. R., Stacker, S. A., Garcia-Aguilar, J.,Hibbs, M. L., and Springer, T. A.
"ICAM-1 CD54: A counter-receptor for Mac-1 CD11b/CD18."
J Cell Biol  111: 3129-3139  (1990).    Pub#: 206  Endnote#: 7131

Springer, T. A.
"The sensation and regulation of interactions with the extracellular environment: The cellbiology of lymphocyte adhesion receptors."
Annu Rev Cell Biol  6: 359-402  (1990).    Pub#: 205  Endnote#: 6992

Johnston, S. C., Dustin, M. L., Hibbs, M. L., and Springer, T. A.
"On the species specificity of the interaction of LFA-1 with intercellular adhesion molecules."
J Immunol  145: 1181-1187  (1990).    Pub#: 204  Endnote#: 6867

Marlin, S. D., Staunton, D. E., Springer, T. A., Stratowa, C., Sommergruber, W., and Merluzzi, V.
"Asoluble form of intercellular adhesion molecule-1 inhibits rhinovirus infection."
Nature  344: 70-72  (1990).    Pub#: 203  Endnote#: 6715

Larson, R. S., and Springer, T. A.
"Structure and function of leukocyte integrins."
Immunol Rev  114: 181-217  (1990).    Pub#: 202  Endnote#: 6851

Larson, R. S., Hibbs, M. L., and Springer, T. A.
"The leukocyte integrin LFA-1 reconstituted by cDNA transfection in a nonhematopoietic cell line is functionally active and not transiently regulated."
Cell Regul  1: 359-367  (1990).    Pub#: 201  Endnote#: 6629

Corbi, A. L., Garcia-Aguilar, J., and Springer, T. A.
"Genomic structure of an integrin a subunit, the leukocyte p150,95 molecule."
J Biol Chem  265: 2782-2788  (1990).    Pub#: 200  Endnote#: 6615

Staunton, D. E., Dustin, M. L., Erickson, H. P., and Springer, T. A.
"The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus."
Cell  61: 243-254  (1990).    Pub#: 199  Endnote#: 6581

Wardlaw, A. J., Hibbs, M. L., Stacker, S. A., and Springer, T. A.
"Distinct mutations in two patients with leukocyte adhesion deficiency and their functional correlates."
J Exp Med  172: 335-345  (1990).    Pub#: 198  Endnote#: 6631

Hibbs, M. L., Wardlaw, A. J., Stacker, S. A., Anderson, D. C., Lee, A., Roberts, T. M., andSpringer, T. A.
"Transfection of cells from patients with leukocyte adhesion deficiency with an integrin b subunit CD18 restores LFA-1 expression and function."
J Clin Invest  85: 674-681  (1990).    Pub#: 197  Endnote#: 6422

Carpen, O., Selvaraj, P., Hibbs, M. L., and Springer, T. A.
"The ability of NK cell and granulocyte forms of CD16 to trigger cytolytic function."
In Natural Killer Cells: Biology and Clinical Application. 6th International Natural Killer Cell Workshop Basel: S. Karger AG  50-54  (1990).    Pub#: 196  Endnote#: 6473

Springer, T. A.
"Adhesion receptors of the immune system."
Nature  346: 425-433  (1990).    Pub#: 195  Endnote#: 5494

Hibbs, M. L., Selvaraj, P., Carpen, O., Springer, T. A., Kuster, H., Jouvin, M. H., and Kinet, J. P.
"Mechanisms for regulating expression of membrane isoforms of Fc gamma RIII CD16."
Science  246: 1608-1611  (1989).    Pub#: 194  Endnote#: 6547

Springer, T. A.
"Adhesion receptors regulate antigen-specific interactions, localization, and differentiation in the immune system."
Progress in Immunology VII  7: 121-130  (1989).    Pub#: 193  Endnote#: 6441

Dustin, M. L., Aguilar, J. G., Hibbs, M. L., Larson, R. S., Stacker, S. A., Staunton, D.E.,Wardlaw, A. J., and Springer, T. A.
"Structure and regulation of the leukocyte adhesion receptor LFA-1 and its counter-receptors, ICAM-1 and ICAM-2."
Cold Spring Harbor Symp. Quant. Biol.  54: 753-765  (1989).    Pub#: 192  Endnote#: 6552

Makgoba, M. W., Sanders, M. E., Luce, G. E. G., Gugel, E. A., Dustin, M. L., Springer, T.A.,and Shaw, S.
"Intercellular Adhesion Molecule-1 ICAM-1 monoclonal antibody inhibits cytotoxic T lymphocyte recognition."
Ann NY Acad Sci  532: 427-428  (1989).    Pub#: 191  Endnote#: 6328

Sanders, M. E., Makgoba, M. W., Sussman, E. H., Luce, G. E. G., Springer, T. A., Cossman,J.,and Shaw, S.
"Spontaneous rosetting of T lymphocytes to Reed-Sternberg cells is mediated by the CD2/LFA-3 and LFA-1/ICAM-1 pathways of antigen-independent adhesion."
Ann NY Acad Sci  532: 436-438  (1989).    Pub#: 190  Endnote#: 6329

Makgoba, M. W., Sanders, M. E., Ginther Luce, G. E., Dustin, M. L., Mannoni, P., Clark, E.A., Springer, T. A., and Shaw, S.
"A cluster of antibodies RR1/1, LB-2 and 84H10 that inhibit LFA-1-dependent lymphoid and myeloid cell adhesion bind intercellular adhesion molecule-1 ICAM-1."
In Immunobiology of HLA Volume II: Immunogenetics and Histocompatibility, B.Dupont, ed.New York: Springer-Verlag  577-580  (1989).    Pub#: 189  Endnote#: 6326

Sanders, M. E., Makgoba, M. W., Sharrow, S. O., Stephany, D., Springer, T. A., Young, H.A.,and Shaw, S.
"Coordinate-enhanced expression of three adhesion molecules LFA-3, CD2, and LFA-1 and three other molecules 4B4, UCHL1, and Pgp-1 defines a human T-cell subset containing memory cells and characterized by enhanced t interferon production."
In Immunobiology of HLA Volume II: Immunogenetics andHistocompatibility, B. Dupont, ed. New York: Springer-Verlag  560-562  (1989).    Pub#: 188  Endnote#: 6325

Dustin, M. L., and Springer, T. A.
"T cell receptor cross-linking transiently stimulates adhesiveness through LFA-1."
Nature  341: 619-624  (1989).    Pub#: 187  Endnote#: 5702

Hollander, N., Low, M. G., and Springer, T. A.
"B cell and activation workshop monoclonal antibodies to phosphatidylinositol-anchored proteins."
In Leukocyte Typing IV, W. Knapp, B. Dorken, W. R. Gilks, E. P. Rieber, R. E. Schmidt, H. Stein and A. E. G. K. von dem Borne, eds. London: Oxford University  182-183  (1989).    Pub#: 186  Endnote#: 6362

Selvaraj, P., Hibbs, M. L., Carpen, O., and Springer, T. A.
"Reactivity of workshop CD16 panel monoclonal antibodies with distinct membrane anchored forms of CD16."
In Leukocyte Typing IV, B. Dorken, W. R. Gilks, E. P. Rieber, R. E. Schmidt, H. Stein and A. E. G. K. von dem Borne, eds. London: Oxford University  595-597  (1989).    Pub#: 185  Endnote#: 6263

Selvaraj, P., Low, M. G., Lopez, P., and Springer, T. A.
"Phosphatidylinositol-anchored antigens definedby non-lineage monoclonal antibodies."
In Leukocyte Typing IV, B. Dorken, W. R. Gilks, E. P. Rieber, R. E. Schmidt, H. Stein and A. E. G. K. von dem Borne, eds. London: Oxford University  743-744  (1989).    Pub#: 184  Endnote#: 6262

Diamond, M. S., Johnston, S. C., Dustin, M. L., McCaffery, P., and Springer, T. A.
"Differential effects on leukocyte functions of CD11a, CD11b, and CD18 monoclonal antibodies."
In Leucocyte Typing IV: White Cell Differentiation Antigens., W. Knapp, B. Dorken, W. R. Gilks, E. P. Rieber, R. E. Schmidt, H. Stein and A.E. G. K.vondem Borne, eds. Oxford:Oxford University Press  570-574  (1989).    Pub#: 183  Endnote#: 6261

Larson, R. S., Hibbs, M. L., Corbi, A. L., Luther, E., Garcia-Aguilar, J., and Springer,T.A.
"The subunit specificity of the CD11a/CD18, CD11b, and CD11c panels of antibodies."
In Leukocyte Typing IV, W. Knapp, B. Dorken, W. R. Gilks, E. P. Rieber, R. E. Schmidt, H. Stein and A. E. G. K. von dem Borne, eds. London: Oxford University  566-570  (1989).    Pub#: 182  Endnote#: 6260

Staunton, D. E., Dustin, M. L., and Springer, T. A.
"Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1."
Nature  339: 61-64  (1989).    Pub#: 181  Endnote#: 6157

Staunton, D. E., Merluzzi, V. J., Rothlein, R., Barton, R., Marlin, S. D., and Springer,T.A.
"A cell adhesion molecule, ICAM-1, is the major surface receptor for rhinoviruses."
Cell  56: 849-853  (1989).    Pub#: 180  Endnote#: 6099

Selvaraj, P., Carpen, O., Hibbs, M. L., and Springer, T. A.
"Natural killer cell and granulocyte Fc gamma receptor III CD16 differ in membrane anchor and signal transduction."
J Immunol  143: 3283-3288  (1989).    Pub#: 179  Endnote#: 6086

Larson, R. S., Corbi, A. L., Berman, L., and Springer, T. A.
"Primary structure of the LFA-1 a subunit: An integrin with an embedded domain defining a protein superfamily."
J Cell Biol  108: 703-712  (1989).    Pub#: 178  Endnote#: 5796

Hollander, N., Shin, M. L., Rosse, W., and Springer, T. A.
"Distinct restriction of complement- and cell-mediated lysis."
J Immunol  142: 3913-3916  (1989).    Pub#: 177  Endnote#: 5804

Kishimoto, T. K., Larson, R. S., Corbi, A. L., Dustin, M. L., Staunton, D. E., and Springer,T. A.
"The leukocyte integrins: LFA-1, Mac-1, and p150,95."
Adv Immunol  46: 149-182  (1989).    Pub#: 176  Endnote#: 5870

Kishimoto, T. K., O'Connor, K., and Springer, T. A.
"Leukocyte adhesion deficiency: Aberrant splicing of a conserved integrin sequence causes a moderate deficiency phenotype."
J Biol Chem  264: 3588-3595  (1989).    Pub#: 175  Endnote#: 5839

Kishimoto, T. K., and Springer, T. A.
"Human leukocyte adhesion deficiency: Molecular basis for a defective immune response to infections of the skin."
In Current Problems in Dermatology, P. Fritsch, G. Schuler and H. Hintner, eds. Basel: Karger  106-115  (1989).    Pub#: 174  Endnote#: 5644

Tonnesen, M. G., Anderson, D. C., Springer, T. A., Knedler, A., Avdi, N., and Henson, P.M.
"Adherence of neutrophils to cultured human microvascular endothelial cells: Dependence upon the Mac-1, LFA-1, p150,95 glycoprotein family."
J Clin Invest  83: 637-646  (1989).    Pub#: 173  Endnote#: 5642

Hale, L. P., Martin, M. E., McCollum, D. E., Nunley, J. A., Springer, T. A., Singer, K. H.,and Haynes, B. F.
"Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment."
Arthritis and Rheumatism  32: 22-30  (1989).    Pub#: 172  Endnote#: 5640

Dustin, M. L., Olive, D., and Springer, T. A.
"Correlation of CD2 binding and functional properties of multimeric and monomeric lymphocyte function associated antigen-3."
J Exp Med  169: 503-517  (1989).    Pub#: 171  Endnote#: 5576

Anderson, D. C., Smith, C. W., and Springer, T. A.
"Disorders of Leukocyte Motility and Adherence."
In Metabolic Basis of Inherited Disease, J. B. Stanbury, J. B. Wyngaarden and D. S. Frederickson, eds. New York: McGraw-Hill  2751-2777  (1989).    Pub#: 170  Endnote#: 5339

Hollander, N., Selvaraj, P., and Springer, T. A.
"Biosynthesis and function of LFA-3 in human mutant cells deficient in phosphatidylinositol anchored proteins."
J Immunol  141: 4283-4290  (1988).    Pub#: 169  Endnote#: 5780

Dustin, M. L., Staunton, D. E., and Springer, T. A.
"Supergene families meet in the immune system."
Immunol Today  9: 213-215  (1988).    Pub#: 168  Endnote#: 5767

Corbi, A. L., Kishimoto, T. K., Miller, L. J., and Springer, T. A.
"The human leukocyte adhesion glycoprotein Mac-1 Complement receptor type 3, CD11b a subunit: Cloning, primary structure, and relation to the integrins, von Willebrand factor and factor B."
J Biol Chem  263: 12403-12411  (1988).    Pub#: 167  Endnote#: 5761

Wang, D., Liebowitz, D., Wang, F., Gregory, C., Rickinson, A., Larson, R. S., Springer, T.A., and Kieff, E.
"Epstein-Barr virus latent infection membrane protein alters the human B lymphocyte phenotype: Deletion of the amino terminus abolishes activity."
J Virol  62: 4173-4184  (1988).    Pub#: 166  Endnote#: 5704

Selvaraj, P., Rosse, W. F., Silber, R., and Springer, T. A.
"The major Fc receptor in blood has a phosphatidylinositol anchor and is deficient in paroxysmal noctural hemoglobinuria."
Nature  333: 565-567  (1988).    Pub#: 165  Endnote#: 5634

Fischer, A., Lisowska-Grospierre, B., Anderson, D. C., and Springer, T. A.
"The leukocyte adhesion deficiency: Molecular basis and functional consequences."
Immunodeficiency Reviews  1: 39-54  (1988).    Pub#: 164  Endnote#: 5605

Staunton, D. E., Marlin, S. D., Stratowa, C., Dustin, M. L., and Springer, T. A.
"Primary structure of intercellular adhesion molecule 1 ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families."
Cell  52: 925-933  (1988).    Pub#: 163  Endnote#: 5607

Corbi, A. L., Larson, R. S., Kishimoto, T. K., Springer, T. A., and Morton, C. C.
"Chromosomal location of the genes encoding the leukocyte adhesion receptors LFA-1, Mac-1 and p150,95. Identification of a gene cluster involved in cell adhesion."
J Exp Med  167: 1597-1607  (1988).    Pub#: 162  Endnote#: 5556

Denning, S. M., Dustin, M. L., Springer, T. A., Singer, K. H., and Haynes, B. F.
"Purified lymphocytefunction-associated antigen-3 LFA-3 activates human thymocytes via the CD2 pathway."
J Immunol  141: 2980-2985  (1988).    Pub#: 161  Endnote#: 5533

Bockenstedt, L. K., Goldsmith, M. A., Dustin, M. L., Olive, D., Springer, T. A., and Weiss,A.
"The CD2 ligand LFA-3 activates T cells but depends on the expression and function of the antigen receptor."
J Immunol  141: 1904-1911  (1988).    Pub#: 160  Endnote#: 5504

Dustin, M. L., and Springer, T. A.
"Lymphocyte function associated antigen-1 LFA-1 interaction with intercellular adhesion molecule-1 ICAM-1 is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells."
J Cell Biol  107: 321-331  (1988).    Pub#: 159  Endnote#: 5497

Dustin, M. L., Singer, K. H., Tuck, D. T., and Springer, T. A.
"Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule-1 ICAM-1."
J Exp Med  167: 1323-1340  (1988).    Pub#: 158  Endnote#: 5477

Mentzer, S. J., Rothlein, R., Springer, T. A., and Faller, D. V.
"Intercellular adhesion molecule-1 ICAM-1 is involved in the cytolytic T lymphocyte interaction with human synovial cells."
J Cell Physiol  137: 173-178  (1988).    Pub#: 157  Endnote#: 5472

Makgoba, M. W., Sanders, M. E., Luce, G. E. G., Dustin, M. L., Springer, T. A., Clark, E.A.,Mannoni, P., and Shaw, S.
"ICAM-1: Definition by multiple antibodies of a ligand for LFA-1 dependent adhesion of B, T and myeloid cell."
Nature  331: 86-88  (1988).    Pub#: 156  Endnote#: 5253

Sanders, M. E., Makgoba, M. W., Sharrow, S. O., Stephany, D., Springer, T. A., Young, H.A.,and Shaw, S.
"Human memory T lymphocytes express increased levels of three cell adhesion molecules LFA-3, CD3, LFA-1 and three other molecules UCHL1, CDw29, and Pgp-1 and have enhanced g interferon production."
J Immunol  140: 1401-1407  (1988).    Pub#: 155  Endnote#: 5235

Cotran, R. S., Pober, J. S., Gimbrone, M. A., Jr., Springer, T. A., Wiebke, E. A., Gaspari,A. A., Rosenberg, S. A., and Lotze, M. T.
"Endothelial activation during interleukin 2 IL 2 immunotherapy: A possible mechanism for the vascular leak syndrome."
J Immunol  140: 1883-1888  (1988).    Pub#: 154  Endnote#: 5210

Makgoba, M. W., Sanders, M. E., Ginther Luce, G. E., Gugel, E. A., Dustin, M. L., Springer,T. A., and Shaw, S.
"Functional evidence that intercellular adhesion molecule-1 ICAM-1 is a ligand for LFA-1 in cytotoxic T cell recognition."
Eur J Immunol  18: 637-640  (1988).    Pub#: 153  Endnote#: 5098

Tiefenthaler, G., Hünig, T., Dustin, M. L., Springer, T. A., and Meuer, S. C.
"Purified lymphocyte function-associated antigen-3 and T11 target structure are active in CD2-mediated T cell stimulation."
Eur J Immunol  17: 1847-1850  (1987).    Pub#: 152  Endnote#: 5250

Marlin, S. D., and Springer, T. A.
"Purified intercellular adhesion molecule-1 ICAM-1 is a ligand for lymphocyte function-associated antigen 1 LFA-1."
Cell  51: 813-819  (1987).    Pub#: 151  Endnote#: 5255

Dustin, M. L., Selvaraj, P., Mattaliano, R. J., and Springer, T. A.
"Anchoring mechanisms for LFA-3 cell adhesion glycoprotein at membrane surface."
Nature  329: 846-848  (1987).    Pub#: 150  Endnote#: 5254

Wallner, B. P., Frey, A. Z., Tizard, R., Mattaliano, R. J., Hession, C., Sanders, M. E.,Dustin, M. L., and Springer, T. A.
"Primary structure of lymphocyte function associated antigen-3 LFA-3: The ligand of the T-lymphocyte CD2 glycoprotein."
J. Exp. Med.  166: 923-934  (1987).    Pub#: 149  Endnote#: 5209

Bainton, D. F., Miller, L. J., Kishimoto, T. K., and Springer, T. A.
"Leukocyte adhesion receptors are stored in peroxidase-negative granules of human neutrophils."
J. Exp. Med.  166: 1641-1653  (1987).    Pub#: 148  Endnote#: 5208

Selvaraj, P., Dustin, M. L., Silber, R., Low, M. G., and Springer, T. A.
"Deficiency of lymphocyte function-associated antigen-3 LFA-3 in paroxysmal nocturnal hemoglobinuria: Functional correlates and evidence for a phosphatidylinositol membrane anchor."
J. Exp. Med.  166: 1011-1025  (1987).    Pub#: 147  Endnote#: 5150

Springer, T. A.
"Immunoaffinity chromatography."
In Current Protocols in Molecular Biology, R. M. Ansubel, R. Brent, R. E. Kingston, D. D. Moore, J. A. Smith, J. G. Seidman and K. Struhl, eds. New York: Greene Publishing Associates  10.11.1-10.11.7, 10.14.1-10.14.6  (1987).    Pub#: 146  Endnote#: 5129

Springer, T. A.
"Purification of Proteins."
In Current Protocols in Molecular Biology, F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. A. Smith, J. G. Seidman and K. Struhl, eds. New York: Greene Publishing Associates  10.16.1-10.16.11  (1987).    Pub#: 145  Endnote#: 5130

Corbi, A. L., Miller, L. J., O'Connor, K., Larson, R. S., and Springer, T. A.
"cDNA cloning and complete primary structure of the a subunit of a leukocyte adhesion glycoprotein, p150,95."
EMBO J.  6: 4023-4028  (1987).    Pub#: 144  Endnote#: 2814

Kishimoto, T. K., Hollander, N., Roberts, T. M., Anderson, D. C., and Springer, T. A.
"Heterogenous mutations in the b subunit common to the LFA-1, Mac-1, and p150,95 glycoproteins cause leukocyte adhesion deficiency."
Cell  50: 193-202  (1987).    Pub#: 143  Endnote#: 24

Tiefenthaler, G., Dustin, M. L., Springer, T. A., and Hünig, T.
"Serological crossreactivity of T11 target structure T11TS and lymphocyte function-associated antigen 3 LFA-3: evidence for structural homology of the sheep and human ligands of CD2."
J. Immunol.  139: 2696-2701  (1987).    Pub#: 142  Endnote#: 5058

Miller, L. J., and Springer, T. A.
"Biosynthesis and glycosylation of p150,95 and related leukocyte adhesion proteins."
J. Immunol.  139: 842-847  (1987).    Pub#: 141  Endnote#: 1933

Pober, J. S., Lapierre, L. A., Stolpen, A. H., Brock, T. A., Springer, T. A., Fiers, W.,Bevilacqua, M. P., Mendrick, D. L., and Gimbrone, M. A., Jr.
"Activation of cultured human endothelial cells by recombinant lymphotoxin: Comparison with tumor necrosis factor and interleukin 1 species."
J. Immunol.  138: 3319-3324  (1987).    Pub#: 140  Endnote#: 1737

Selvaraj, P., Dustin, M. L., Mitnacht, R., Hünig, T., Springer, T. A., and Plunkett,M.L.
"Rosetting of human T-lymphocytes with sheep and human erythrocytes: Comparison of human and sheep ligand binding using purified E receptor."
J. Immunol.  139: 2690-2695  (1987).    Pub#: 139  Endnote#: 1697

Borregaard, N., Miller, L. J., and Springer, T. A.
"Chemoattractant-regulated fusion of a novel, mobilizable intracellular compartment with the plasma membrane in human neutrophils."
Science  237: 1204-1206  (1987).    Pub#: 138  Endnote#: 1452

Dustin, M. L., Sanders, M. E., Shaw, S., and Springer, T. A.
"Purified lymphocyte function-associated antigen-3 LFA-3 binds to CD2 and mediates T lymphocyte adhesion."
J. Exp. Med.  165: 677-692  (1987).    Pub#: 137  Endnote#: 3

Pischel, K. D., Marlin, S. D., Springer, T. A., Woods, V. L., Jr., and Bluestein, H. G.
"Polymorphism of lymphocyte function associated antigen-1, LFA-1, demonstrated by a Lupus patient's alloantiserum."
J. Clin. Invest.  79: 1607-1614  (1987).    Pub#: 136  Endnote#: 3081

Selvaraj, P., Plunkett, M. L., Dustin, M. L., Sanders, M. E., Shaw, S., and Springer, T.A.
"The T lymphocyte glycoprotein CD2 LFA-2/T11/E-Rosette receptor binds the cell surface ligand LFA-3."
Nature  326:400-403  (1987).    Pub#: 135  Endnote#: 5007

Kishimoto, T. K., Miller, L. J., and Springer, T. A.
"Homology of LFA-1, Mac-1, and p150,95 with the extracellular matrix receptors defines a novel supergene family of adhesion proteins."
In Leukocyte Typing III, A. McMichael, ed. New York: Springer-Verlag    (1987).    Pub#: 134  Endnote#: 0

Kishimoto, T. K., O'Connor, K., Lee, A., Roberts, T. M., and Springer, T. A.
"Cloning of the b subunit of the leukocyte adhesion proteins: Homology to an extracellular matrix receptor defines a novel supergene family."
Cell  48: 681-690  (1987).    Pub#: 133  Endnote#: 4945

Miller, L. J., Wiebe, M., and Springer, T. A.
"Purification and a subunit N-terminal sequences of human Mac-1 and p150,95 leukocyte adhesion proteins."
J. Immunol.  138: 2381-2383  (1987).    Pub#: 132  Endnote#: 4953

Shaw, S., Luce, G. G., Springer, T. A., Plunkett, M. L., Quinones, R., Gress, R. E., andSanders, M. E.
"Human cytotoxic T cells adhere to potential targets by two antigen-independent pathways: CD2 binding to LFA-3 or LFA-1 binding to an undefined ligand."
In Leukocyte Typing III, A. McMichael, ed. New York: Springer-Verlag  137-139  (1987).    Pub#: 131  Endnote#: 5040

Miller, L. J., Bainton, D. F., Borregaard, N., and Springer, T. A.
"Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface."
J. Clin. Invest.  80: 535-544  (1987).    Pub#: 130  Endnote#: 5039

Springer, T. A., Dustin, M. L., Kishimoto, T. K., and Marlin, S. D.
"The lymphocyte function-associated LFA-1, CD2, and LFA-3 molecules: cell adhesion receptors of the immune system."
Annu. Rev. Immunol.  5: 223-252  (1987).    Pub#: 129  Endnote#: 4863

Anderson, D. C., and Springer, T. A.
"Leukocyte adhesion deficiency: An inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins."
Ann. Rev. of Med.  38: 175-194  (1987).    Pub#: 128  Endnote#: 4883

Plunkett, M. L., Sanders, M. E., Selvaraj, P., Dustin, M. L., and Springer, T. A.
"Rosetting of activated human T lymphocytes with autologous erythrocytes: Definition of the receptor and ligand molecules as CD2 and lymphocyte function-associated antigen 3 LFA-3."
J. Exp. Med.  165: 664-676  (1987).    Pub#: 127  Endnote#: 5008

Denning, S. M., Tuck, D. T., Vollger, L. W., Springer, T. A., Singer, K. H., and Haynes,B.F.
"Monoclonal antibodies to CD-2 and lymphocyte function-associated antigen 3 inhibit human thymic epithelial cell-dependent mature thymocyte activation."
J. Immunol.  139: 2573-2578  (1987).    Pub#: 126  Endnote#: 4881

Vollger, L. W., Tuck, D. T., Springer, T. A., Haynes, B. F., and Singer, K. H.
"Thymocyte binding to human thymic epithelial cells is inhibited by monoclonal antibodies to CD-2 and LFA-3 antigens."
J. Immunol.  138: 358-363  (1987).    Pub#: 125  Endnote#: 4773

Haskard, D., Cavender, D., Beatty, P., Springer, T. A., and Ziff, M.
"T lymphocyte adhesion to endothelial cells: Mechanisms demonstrated by anti-LFA-1 monoclonal antibodies."
J. Immunol.  137: 2901-2906  (1986).    Pub#: 124  Endnote#: 5385

Shaw, S., Luce, G. E. G., Quinones, R., Gress, R. E., Springer, T. A., and Sanders, M. E.
"Two antigen-independent adhesion pathways used by human cytotoxic T cell clones."
Nature  323: 262-264  (1986).    Pub#: 123  Endnote#: 4774

Miller, L. J., Schwarting, R., and Springer, T. A.
"Regulated expression of the Mac-1, LFA-1, p150,95 glycoprotein family during leukocyte differentiation."
J. Immunol.  137: 2891-2900  (1986).    Pub#: 122  Endnote#: 4772

Mentzer, S. J., Bierer, B. E., Anderson, D. C., Springer, T. A., and Burakoff, S. J.
"Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones."
J. Clin. Invest.  78: 1387-1391  (1986).    Pub#: 121  Endnote#: 4729

Pober, J. S., Gimbrone, M. A., Jr., Lapierre, L. A., Mendrick, D. L., Fiers, W., Rothlein,R., and Springer, T. A.
"Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor and immune interferon."
J. Immunol.  137: 1893-1896  (1986).    Pub#: 120  Endnote#: 4764

Marlin, S. D., Morton, C. C., Anderson, D. C., and Springer, T. A.
"LFA-1 immunodeficiency disease: Definition of the genetic defect and chromosomal mapping of a and b subunits of the lymphocyte function-associated antigen 1 LFA-1 by complementation in hybrid cells."
J. Exp. Med.  164: 855-867  (1986).    Pub#: 119  Endnote#: 4748

Gee, C. E., Griffin, J., Sastre, L., Miller, L. J., Springer, T. A., Piwnica-Worms, H., andRoberts, T. M.
"Differentiation of myeloid cells is accompanied by increased levels of pp60c-src protein and kinase activity."
Proc. Natl. Acad. Sci. U.S.A.  83: 5131-5135  (1986).    Pub#: 118  Endnote#: 4771

Plunkett, M. L., and Springer, T. A.
"Purification and characterization of the lymphocyte function-associated-2 LFA-2 molecule."
J. Immunol.  136: 4181-4187  (1986).    Pub#: 117  Endnote#: 4750

Sastre, L., Kishimoto, T. K., Gee, C., Roberts, T., and Springer, T. A.
"The mouse leukocyte adhesion proteins Mac-1 and LFA-1: Studies on mRNA translation and protein glycosylation with emphasis on Mac-1."
J. Immunol.  137: 1060-1065  (1986).    Pub#: 116  Endnote#: 4704

Sastre, L., Roman, J. M., Teplow, D. B., Dreyer, W. J., Gee, C. E., Larson, R. S., Roberts,T. M., and Springer, T. A.
"A partial genomic DNA clone for the a subunit of the mouse complement receptor type 3 and cellular adhesion molecule Mac-1."
Proc. Natl. Acad. Sci. U.S.A.  83: 5644-5648  (1986).    Pub#: 115  Endnote#: 4703

Strassmann, G., Somers, S. D., Springer, T. A., Adams, D. O., and Hamilton, T. A.
"Biochemical models of interferon gamma mediated macrophage activation. Independent regulation of lymphocyte function associated antigen LFA-1 and I-A antigen on murine peritoneal macrophages."
Cell. Immunol.  97: 110-120  (1986).    Pub#: 114  Endnote#: 4642

Anderson, D. C., Miller, L. J., Schmalstieg, F. C., Rothlein, R., and Springer, T. A.
"Contributions of the Mac-1 glycoprotein family to adherence-dependent granulocyte functions: Structure-function assessments employing subunit-specific monoclonal antibodies."
J. Immunol.  137: 15-27  (1986).    Pub#: 113  Endnote#: 4641

Strassmann, G., Springer, T. A., Somers, S. D., and Adams, D. O.
"Mechanisms of tumor cell capture by activated macrophages: Evidence for involvement of lymphocyte function associated LFA-1 antigen."
J. Immunol.  136: 4328-4333  (1986).    Pub#: 112  Endnote#: 4640

Dustin, M. L., Rothlein, R., Bhan, A. K., Dinarello, C. A., and Springer, T. A.
"Induction by IL-1 and interferon, tissue distribution, biochemistry, and function of a natural adherence molecule ICAM-1."
J. Immunol.  137: 245-254  (1986).    Pub#: 111  Endnote#: 4582

Rothlein, R., Dustin, M. L., Marlin, S. D., and Springer, T. A.
"A human intercellular adhesion molecule ICAM-1 distinct from LFA-1."
J. Immunol.  137: 1270-1274  (1986).    Pub#: 110  Endnote#: 4605

Rothlein, R., and Springer, T. A.
"The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester."
J. Exp. Med.  163: 1132-1149  (1986).    Pub#: 109  Endnote#: 4513

Springer, T. A., Miller, L. J., and Anderson, D. C.
"p150,95, the third member of the Mac-1, LFA-1 human leukocyte adhesion glycoprotein family."
J. Immunol.  136: 240-245  (1986).    Pub#: 108  Endnote#: 4483

Springer, T. A., and Anderson, D. C.
"Leukocyte complement receptors and adhesion proteins in the inflammatory response: Insights from an experiment of nature."
In Genes and Proteins in Immunity, Biochem. Soc. Symp.51, J. Kay, M. A. Kerr, A. F. Williams and K. B. M. Reid,eds. London: A. R. Liss  47-57  (1986).    Pub#: 107  Endnote#: 4482

Lisowska-Grospierre, B., Bohler, M. C., Fischer, A., Mawas, C., Springer, T. A., and Griscelli, C.
"Defective membrane expression of the LFA-1 complex may be secondary to the absence of the b chain in a child with recurrent bacterial infection."
Eur. J. Immunol.  16: 205-208  (1986).    Pub#: 106  Endnote#: 4411

Springer, T. A., and Anderson, D. C.
"The importance of the Mac-1, LFA-1 glycoprotein family in monocyte and granulocyte adherence, chemotaxis, and migration into inflammatory sites: Insights from an experiment of nature."
In Biochemistry of Macrophages Ciba Symposium 118 London: Pitman  102-126  (1986).    Pub#: 105  Endnote#: 4341

Cardosa, M. J., Gordon, S., Hirsch, S., Springer, T. A., and Porterfield, J. S.
"Interaction of West Nile virus with primary murine macrophages: Role of cell activation and receptors for antibody and complement."
J. Virol.  57: 952-959  (1986).    Pub#: 104  Endnote#: 4349

Sanchez-Madrid, F., and Springer, T. A.
"Production of syrian and armenian hamster monoclonal antibodies of defined specificity."
Methods Enzymol.  121: 239-244  (1986).    Pub#: 103  Endnote#: 3553

Unkeless, J. C., and Springer, T. A.
"Macrophages."
In Handbook of experimental immunology, 4th ed. Vol.IV: Applications of immunological methods in biomedical sciences, D. M. Weir, L. A. Herzenberg and C. C. Blackwell, eds. Oxford: Blackwell  118  (1986).    Pub#: 102  Endnote#: 3821

Springer, T. A., and Anderson, D. C.
"Antibodies specific for the Mac-1, LFA-1, p150,95 glycoproteins or their family, or for other granulocyte proteins, in the 2nd International Workshop on Human Leukocyte Differentiation Antigens."
In Human Myeloid and Hematopoietic Cells, E. L. Reinherz, B. F. Haynes, L.M. Nadler and I. D. Bernstein, eds. New York: Springer-Verlag  55-68  (1986).    Pub#: 101  Endnote#: 4207

Strassmann, G., Springer, T. A., Haskill, S. J., Miraglia, C. C., Lanier, L. L., and Adams,D. O.
"Antigens associated with the activation of murine mononuclear phagocytes in vivo: Differential expression of lymphocyte function-associated antigen in the several stages of development."
Cell. Immunol.  94: 265-275  (1985).    Pub#: 100  Endnote#: 3873

Krensky, A. M., Mentzer, S. J., Clayberger, C., Anderson, D. C., Schmalstieg, F. C., Burakoff, S. J., and Springer, T. A.
"Heritable lymphocyte function-associated antigen-1 deficiency: Abnormalities of cytotoxicity and proliferation associated with abnormal expression of LFA-1."
J. Immunol.  135: 3102-3108  (1985).    Pub#: 99  Endnote#: 4424

Anderson, D. C., and Springer, T. A.
"The importance of the Mac-1, LFA-1 glycoprotein family in adherence-dependent inflammatory functions: Insights from an experiment of nature."
In Infection and Malignancy RES Symposium New York: Alan Liss    (1985).    Pub#: 98  Endnote#: 4423

Gaulton, G. N., Bangs, J., Maddock, S., Springer, T. A., Eardley, D. D., and Strom, T. B.
"Characterization of a monoclonal rat anti-mouse interleukin 2 IL-2 receptor antibody and its use in the biochemical characterization of the murine IL-2 receptor."
Clin. Immunol. Immunopathol.  36: 18-29  (1985).    Pub#: 97  Endnote#: 4385

Rothlein, R., and Springer, T. A.
"Complement receptor type three-dependent degradation of opsonized erythrocytes by mouse macrophages."
J. Immunol.  135: 2668-2672  (1985).    Pub#: 96  Endnote#: 4305

Strassmann, G., Springer, T. A., and Adams, D. O.
"Studies on antigens associated with the activation of murine mononuclear phagocytes: Kinetics of and requirements for induction of lymphocyte function-associated LFA-1 Antigen in vitro."
J. Immunol.  135: 147-151  (1985).    Pub#: 95  Endnote#: 4350

Shaw, S., Goldstein, G., Springer, T. A., and Biddison, W. E.
"Susceptibility of cytotoxic T lymphocyte CTL clones to inhibition by anti-T3 and anti-T4 but not anti-LFA-1 monoclonal antibodies varies with the "avidity" of CTL-target interaction."
J. Immunol.  134: 3019-3026  (1985).    Pub#: 94  Endnote#: 4328

Hogarth, P. M., Walker, I. D., McKenzie, I. F. C., and Springer, T. A.
"The Ly-15 alloantigenic system: A genetically determined polymorphism of the murine lymphocyte function-associated antigen-1 molecule."
Proc. Natl. Acad. Sci. U. S. A.  82: 526-530  (1985).    Pub#: 93  Endnote#: 4221

Springer, T. A., Teplow, D. B., and Dreyer, W. J.
"Sequence homology of the LFA-1 and Mac-1 leukocyte adhesion glycoproteins and unexpected relation to leukocyte interferon."
Nature  314: 540-542  (1985).    Pub#: 92  Endnote#: 3313

Krensky, A. M., Mentzer, S. J., Greenstein, J. L., Crimmins, M., Clayberger, C., Springer, T. A., and Burakoff, S. J.
"Human cytolytic T-lymphocyte clones and their function-associated cell surface molecules."
In Hybridoma Technology in the Biosciences and Medicine, T. A. Springer, ed. New York and London: Plenum Press  559-573  (1985).    Pub#: 91  Endnote#: 4164

Springer, T. A., and Anderson, D. C.
"Functional and structural interrelationships among the Mac-1, LFA-1 family of leukocyte adhesion glycoproteins, and their deficiency in a novel, heritable disease."
In Hybridoma Technology in the Biosciences and Medicine, T. A. Springer, ed. NewYork and London: Plenum Press  191-206  (1985).    Pub#: 90  Endnote#: 4206

Anderson, D. C., Schmalsteig, F. C., Finegold, M. J., Hughes, B. J., Rothlein, R., Miller, L. J., Kohl, S., Tosi, M. F., Jacobs, R. L., Waldrop, T. C., Goldman, A. S., Shearer, W. T., and Springer, T. A.
"The severe and moderate phenotypes of heritable Mac-1, LFA-1 deficiency: Their quantitative definition and relation to leukocyte dysfunction and clinical features."
J. Infect. Dis.  152: 668-689  (1985).    Pub#: 89  Endnote#: 4205

Springer, T. A., Rothlein, R., Anderson, D. C., Burakoff, S. J., and Krensky, A. M.
"The function of LFA-1 in cell-mediated killing and adhesion: Studies on heritable LFA-1, Mac-1 deficiency and on lymphoid cell self-aggregation."
In Mechanisms of Cell-Mediated Cytotoxicity II, P. Henkart and E. Martz, eds. New York, London: Plenum Press  311-322  (1985).    Pub#: 88  Endnote#: 88

Miller, B. A., Antognetti, G., and Springer, T. A.
"Identification of cell surface antigens present on murine hematopoietic stem cells."
J. Immunol.  134: 3286-3290  (1985).    Pub#: 87  Endnote#: 4306

Ross, G. D., Thompson, R. A., Walport, M. J., Springer, T. A., Watson, J. V., Ward, R. H. R., Lida, J., Newman, S. L., Harrison, R. A., and Lachmann, P. J.
"Characterization of patients with an increased susceptibility to bacterial infections and a genetic deficiency of leukocyte membrane complement receptor type 3 and the related membrane antigen LFA-1."
Blood  66: 882-890  (1985).    Pub#: 86  Endnote#: 4151

Fischer, A., Seger, R., Durandy, A., Grospierre, B., Virelizier, J. L., Le Deist, F., Griscelli, C., Fischer, E., Kazatchkine, M., Bohler, M.-C., Descamps-Latscha, B., Trung, P. H., Springer, T. A., Olive, D., and Mawas, C.
"Deficiency of the adhesive protein complex lymphocyte function antigen 1, complement receptor type 3, glycoprotein p150,95 in a girl with recurrent bacterial infections."
J. Clin. Invest.  76: 2385-2392  (1985).    Pub#: 85  Endnote#: 4153

Springer, T. A., Sastre, L., and Anderson, D. C.
"The LFA-1, Mac-1 leukocyte adhesion glycoprotein family and its deficiency in a heritable human disease."
Biochem. Soc. Trans.  13: 3-6  (1985).    Pub#: 84  Endnote#: 4173

Springer, T. A., Sastre, L., Schmalstieg, F., and Anderson, D.
"Inherited LFA-1, Mac-1 deficiency and its molecular biology."
In Mononuclear Phagocytes: Physiology and Function, R. van Furth, ed. Dordrecht, Boston, Lancaster: Martinus Nijhoff  115-123  (1985).    Pub#: 83  Endnote#: 4162

Anderson, D. C., Schmalstieg, F. C., Shearer, W., Becker-Freeman, K., Kohl, S., Smith, C. W., Tosi, M. F., and Springer, T. A.
"Leukocyte LFA-1, OKM1, p150,95 deficiency syndrome: functional and biosynthetic studies in three kindreds."
Fed. Proc.  44: 2671-2677  (1985).    Pub#: 82  Endnote#: 4150

Springer, T. A.
"The LFA-1, Mac-1 glycoprotein family and its deficiency in an inherited disease."
Fed. Proc.  44: 2660-2663  (1985).    Pub#: 81  Endnote#: 4147

Krensky, A. M., Clayberger, C., Greenstein, J. L., Collins, T., Pober, J. S., Robbins, E., Anderson, D., Springer, T. A., and Burakoff, S. J.
"Cell surface structures involved in the human cytolytic T lymphocyte response."
In Regulation of the Immune System, E. Sercarz, H. Cantor and L. Chess, eds. New York: Alan R. Liss  209-219  (1984).    Pub#: 80  Endnote#: 2972

Springer, T. A., Thompson, W. S., Miller, L. J., Schmalstieg, F. C., and Anderson, D. C.
"Inherited deficiency of the Mac-1, LFA-1, p150,95 glycoprotein family and its molecular basis."
J. Exp. Med.  160: 1901-1918  (1984).    Pub#: 79  Endnote#: 4163

Kohl, S., Springer, T. A., Schmalstieg, F. C., Loo, L. S., and Anderson, D. C.
"Defective natural killer cytotoxicity and polymorphonuclear leukocyte antibody-dependent cellular cytotoxicity in patients with LFA-1/OKM-1 deficiency."
J. Immunol.  133: 2972-2978  (1984).    Pub#: 78  Endnote#: 3377

Anderson, D. C., Schmalstieg, F. C., Arnaout, M. A., Kohl, S., Tosi, M. F., Dana, N., Buffone, G. J., Hughes, B. J., Brinkley, B. R., Dickey, W. D., Abramson, J. S., Springer, T. A., Boxer, L. A., Hollers, J. M., and Smith, C. W.
"Abnormalities of polymorphonuclear leukocyte function associated with a heritable deficiency of high molecular weight surface glycoproteins GP138: Common relationship to diminished cell adherence."
J. Clin. Invest.  74: 536-551  (1984).    Pub#: 77  Endnote#: 4055

Hemler, M. E., Sanchez-Madrid, F., Flotte, T. J., Krensky, A. M., Burakoff, S. J., Bhan, A. K., Springer, T. A., and Strominger, J. L.
"Glycoproteins of 210,000 and 130,000 M.W. on activated T cells: Cell distribution and antigenic relation to components on resting cells and T cell lines."
J. Immunol.  132: 3011-3018  (1984).    Pub#: 76  Endnote#: 4003

Krensky, A. M., Robbins, E., Springer, T. A., and Burakoff, S. J.
"LFA-1, LFA-2 and LFA-3 antigens are involved in CTL-target conjugation."
J. Immunol.  132: 2180-2182  (1984).    Pub#: 75  Endnote#: 4143

Krensky, A. M., Sanchez-Madrid, F., Springer, T. A., and Burakoff, S. J.
"Human lymphocyte function associated antigens."
Surv. Immunologic Res.  3: 39-44  (1984).    Pub#: 74  Endnote#: 4081

Dana, N., Todd, R. F., III, Pitt, J., Springer, T. A., and Arnaout, M. A.
"Deficiency of a surface membrane glycoprotein Mo1 in man."
J. Clin. Invest.  73: 153-159  (1984).    Pub#: 73  Endnote#: 3874

Ho, M., and Springer, T. A.
"Preparation and use of monoclonal antimacrophage antibodies."
Methods Enzymol.  108: 313-324  (1984).    Pub#: 72  Endnote#: 3546

Springer, T. A., and Unkeless, J. C.
"Analysis of macrophage differentiation and function with monoclonal antibodies."
In Contemporary Topics in Immunobiology, Vol.14, D. O. Adams and M. G. Hanna, Jr., eds. New York: Plenum Press  38748  (1984).    Pub#: 71  Endnote#: 3544

Springer, T. A.
"Macrophage and T lymphocyte-mediated immunity: Similarities at the level of the Mac-1 and LFA-1 molecules."
In Mononuclear Phagocyte Biology, A. Volkman, ed. New York: Marcel Dekker  109-128  (1984).    Pub#: 70  Endnote#: 3384

Flotte, T. J., Haines, K. A., Pechman, K. M., Springer, T. A., Gigli, I., and Thorbecke, G. J.
"The relation of Langerhans cells to other dendritic cells and macrophages."
In Mononuclear Phagocyte Biology, A. Volkman, ed. New York: Marcel Dekker, New York  51-66  (1984).    Pub#: 69  Endnote#: 3223

Sanchez-Madrid, F., Nagy, J., Robbins, E., Simon, P., and Springer, T. A.
"A human leukocyte differentiation antigen family with distinct a subunits and a common b subunit: The lymphocyte function-associated antigen LFA-1, the C3bi complement receptor OKM1/Mac-1, and the p150,95 molecule."
J. Exp. Med.  158: 1785-1803  (1983).    Pub#: 68  Endnote#: 3716

Ware, C. F., Sanchez-Madrid, F., Krensky, A. M., Burakoff, S. J., Strominger, J. L., and Springer, T. A.
"Human lymphocyte function associated antigen-1 LFA-1: identification of multiple antigenic epitopes and their relationship to CTL-mediated cytotoxicity."
J. Immunol.  131: 1182-1187  (1983).    Pub#: 67  Endnote#: 3608

Sanchez-Madrid, F., Simon, P., Thompson, S., and Springer, T. A.
"Mapping of antigenic and functional epitopes on the a and b subunits of two related glycoproteins involved in cell interactions, LFA-1 and Mac-1."
J. Exp. Med.  158: 586-602  (1983).    Pub#: 66  Endnote#: 3294

Ralph, P., Harris, P., Punjabi, C. J., Welte, K., Litcofsky, P. B., Ho, M.-K., Rubin, B., Moore, M. A. S., and Springer, T. A.
"Lymphokine inducing "terminal differentiation" of the human monoblast leukemia line U937: a role for g interferon."
Blood  62: 1169-1175  (1983).    Pub#: 65  Endnote#: 3543

Krensky, A. M., Sanchez-Madrid, F., Robbins, E., Nagy, J., Springer, T. A., and Burakoff, S. J.
"The functional significance, distribution, and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target interactions."
J. Immunol.  131: 611-616  (1983).    Pub#: 64  Endnote#: 3540

Burakoff, S. J., Clayberger, C., Hemler, M., Krensky, A. M., Reiss, C. S., Robbins, E., Sanchez-Madrid, F., Springer, T. A., Strominger, J. L., and Ware, C. F.
"Cytotoxic T cells directed against HLA-DR antigens and their surface proteins."
Diag. Immunol.  3: 116-119  (1983).    Pub#: 63  Endnote#: 3604

Gromkowski, S. H., Heagy, W. E., Sanchez-Madrid, F., Springer, T. A., and Martz, E.
"Blocking of CTL-mediated killing by monoclonal antibodies to LFA-1 and Lyt-2,3. I: Increased susceptibility to blocking after papain treatment of target cells."
J. Immunol.  130: 2546-2551  (1983).    Pub#: 62  Endnote#: 3385

Haines, K. A., Flotte, T. J., Springer, T. A., Gigli, I., and Thorbecke, G. J.
"Staining of Langerhans cells with monoclonal antibodies to macrophages and lymphoid cells."
Proc. Natl. Acad. Sci. U.S.A.  80: 3448-3451  (1983).    Pub#: 61  Endnote#: 3386

Ho, M.-K., and Springer, T. A.
"Biosynthesis and assembly of the a and b subunits of Mac-1, a macrophage glycoprotein associated with complement receptor function."
J. Biol. Chem.  258: 2766-2769  (1983).    Pub#: 60  Endnote#: 3312

Ho, M.-K., and Springer, T. A.
"Tissue distribution, structural characterization and biosynthesis of Mac-3, a macrophage surface glycoprotein exhibiting molecular weight heterogeneity."
J. Biol. Chem.  258: 636-642  (1983).    Pub#: 59  Endnote#: 3260

Baldwin, W. M., III, Claas, F. H. J., Paul, L. C., Springer, T. A., Hendriks, G. F. J., van Es, L. A., and Van Rood, J. J.
"All monocyte antigens are not expressed on renal endothelium."
Tissue Antigens  21: 254-259  (1983).    Pub#: 58  Endnote#: 3464

Mendrick, D. L., Rennke, H. G., Cotran, R. S., Springer, T. A., and Abbas, A. K.
"Monoclonal antibodies against rat glomerular antigens: production and specificity."
Lab. Invest.  49: 107-117  (1983).    Pub#: 57  Endnote#: 3224

Ralph, P., Ho, M.-K., Litcofsky, P. B., and Springer, T. A.
"Expression and induction in vitro of macrophage differentiation antigens on murine cell lines."
J. Immunol.  130: 108-114  (1983).    Pub#: 56  Endnote#: 3226

Sanchez-Madrid, F., Szklut, P., and Springer, T. A.
"Stable hamster-mouse hybridomas producing IgG and IgM hamster monoclonal antibodies of defined specificity."
J. Immunol.  130: 309-312  (1983).    Pub#: 55  Endnote#: 3257

Flotte, T., Springer, T. A., and Thorbecke, G. J.
"Dendritic cell and macrophage staining by monoclonal antibodies in tissue sections and epidermal sheets."
Am. J. Pathol.  111: 112-124  (1983).    Pub#: 54  Endnote#: 3078

Springer, T. A.
"Quantitation of hybridoma immunoglobulins and selection of myeloma or specific light chain loss variants."
Methods Enzymol.  92: 147-160  (1983).    Pub#: 53  Endnote#: 2961

Weinberger, O., Germain, R. N., Springer, T. A., and Burakoff, S. J.
"Role of syngeneic Ia accessory cells in the generation of allospecific CTL responses."
J. Immunol.  129: 694-697  (1982).    Pub#: 52  Endnote#: 3285

Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., and Springer, T. A.
"Three distinct antigens associated with human T lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3."
Proc. Natl. Acad. Sci. U.S.A.  79: 7489-7493  (1982).    Pub#: 51  Endnote#: 3259

Kaufman, Y., Golstein, P., Pierres, M., Springer, T. A., and Eshhar, Z.
"LFA-1 but not Lyt-2 is associated with killing activity of cytotoxic T lymphocyte hybridomas."
Nature  300: 357-360  (1982).    Pub#: 50  Endnote#: 3256

Springer, T. A., Davignon, D., Ho, M. K., Kürzinger, K., Martz, E., and Sanchez-Madrid, F.
"LFA-1 and Lyt-2,3, molecules associated with T lymphocyte-mediated killing; and Mac-1, an LFA-1 homologue associated with complement receptor function."
Immunol. Rev.  68: 171-195  (1982).    Pub#: 49  Endnote#: 3107

Beller, D. I., Springer, T. A., and Schreiber, R. D.
"Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor."
J. Exp. Med.  156: 1000-1009  (1982).    Pub#: 48  Endnote#: 3077

Sanchez-Madrid, F., Davignon, D., Martz, E., and Springer, T. A.
"Antigens involved in mouse cytolytic T-lymphocyte CTL-mediated killing: functional screening and topographic relationship."
Cell. Immunol.  73: 1-11  (1982).    Pub#: 47  Endnote#: 3076

Kürzinger, K., and Springer, T. A.
"Purification and structural characterization of LFA-1, a lymphocyte function-associated antigen, and Mac-1, a related macrophage differentiation antigen."
J. Biol. Chem.  257: 12412-12418  (1982).    Pub#: 46  Endnote#: 2999

Springer, T. A., Bhattacharya, A., Cardoza, J. T., and Sanchez-Madrid, F.
"Monoclonal antibodies specific for rat IgG1, IgG2a, and IgG2b subclasses, and k chain monotypic and allotypic determinants: Reagents for use with rat monoclonal antibodies."
Hybridoma  I: 257-273  (1982).    Pub#: 45  Endnote#: 2916

Ho, M. K., and Springer, T. A.
"Mac-1 antigen: Quantitative expression in macrophage populations and tissues, and immunofluorescent localization in spleen."
J. Immunol.  128: 2281-2286  (1982).    Pub#: 44  Endnote#: 2960

Martz, E., Davignon, D., Kürzinger, K., and Springer, T. A.
"The molecular basis for cytolytic T lymphocyte function: Analysis with blocking monoclonal antibodies."
Adv. Exper. Med. Biol.  146: 447-465  (1982).    Pub#: 43  Endnote#: 2959

Germain, R. N., Bhattacharya, A., Dorf, M. E., and Springer, T. A.
"A single monoclonal anti-Ia antibody inhibits antigen-specific T cell proliferation controlled by distinct Ir genes mapping in different H-2 I subregions."
J. Immunol.  128: 1409-1413  (1982).    Pub#: 42  Endnote#: 2832

Springer, T. A., and Ho, M.-K.
"Macrophage differentiation antigens: markers for macrophage subpopulations and tissue localization."
In Hybridomas in cancer diagnosis and treatment, M. S. Mitchell and H. F. Oettgen, eds. New York: Raven Press  53-61  (1982).    Pub#: 41  Endnote#: 2624

Kürzinger, K., Ho, M. K., and Springer, T. A.
"Structural homology of a macrophage differentiation antigen and an antigen involved in T-cell-mediated killing."
Nature  296: 668-670  (1982).    Pub#: 40  Endnote#: 2623

Springer, T. A.
"Murine macrophage differentiation antigens defined by monoclonal antibodies."
In Monoclonal hybridoma antibodies: techniques and applications, J. G. R. Hurrel, ed. New York.: CRC Press  169-175  (1982).    Pub#: 39  Endnote#: 2584

Ho, M. K., and Springer, T. A.
"Mac-2, a novel 32,000 Mr macrophage subpopulation-specific antigen defined by monoclonal antibody."
J. Immunol.  128: 1221-1228  (1982).    Pub#: 38  Endnote#: 2363

Bhattacharya, A., Dorf, M. E., and Springer, T. A.
"A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication."
J. Immunol.  127: 2488-2495  (1981).    Pub#: 37  Endnote#: 2815

Holmberg, L. A., Springer, T. A., and Ault, K. A.
"Natural killer activity in the peritoneal exudates of mice infected with Listeria monocytogenes: Characterization of the natural killer cells by using a monoclonal rat anti-murine macrophage antibody M1/70."
J. Immunol.  127: 1792-1799  (1981).    Pub#: 36  Endnote#: 2529

Stallcup, K. C., Springer, T. A., and Mescher, M. F.
"Characterization of an anti-H-2 monoclonal antibody and its use in large-scale antigen purification."
J. Immunol.  127: 923-930  (1981).    Pub#: 35  Endnote#: 2395

Ho, M. K., and Springer, T. A.
"Rat anti-mouse macrophage monoclonal antibodies and their use in immunofluorescent studies of macrophages in tissue sections."
In Monoclonal antibodies and T cell hybridomas, U. Hammerling, G. Hammerling and J. Kearney, eds. New York:Elsevier  53-61  (1981).    Pub#: 34  Endnote#: 2362

Kürzinger, K., Reynolds, T., Germain, R. N., Davignon, D., Martz, E., and Springer, T. A.
"A novel lymphocyte function-associated antigen LFA-1: cellular distribution, quantitative expression, and structure."
J. Immunol.  127: 596-602  (1981).    Pub#: 33  Endnote#: 696

Davignon, D., Martz, E., Reynolds, T., Kürzinger, K., and Springer, T. A.
"Monoclonal antibody to a novel lymphocyte function-associated antigen LFA-1: Mechanism of blocking of T lymphocyte-mediated killing and effects on other T and B lymphocyte functions."
J. Immunol.  127: 590-595  (1981).    Pub#: 32  Endnote#: 821

Springer, T. A.
"Monoclonal antibodies as tools for the study of mononuclear phagocytes."
In Methods for studying mononuclear phagocytes, D. O. Adams, P. J. Edelson and H. Koren, eds. New York: Academic Press  305-313  (1981).    Pub#: 31  Endnote#: 2435

Springer, T. A., Kürzinger, K., Reynolds, T., Germain, R. N., Davignon, D., and Martz, E.
"Monoclonal antibodies as probes of surface structures participating in T-lymphocyte function."
In Monoclonal antibodies and T cell hybridomas, U. Hammerling, G. Hammerling and J. Kearney, eds. New York: Elsevier  45-52  (1981).    Pub#: 30  Endnote#: 2361

Davignon, D., Martz, E., Reynolds, T., Kürzinger, K., and Springer, T. A.
"Lymphocyte function-associated antigen 1 LFA-1: A surface antigen distinct from Lyt-2,3 that participates in T lymphocyte-mediated killing."
Proc. Natl. Acad. Sci. U. S. A.  78: 4535-4539  (1981).    Pub#: 29  Endnote#: 2360

Springer, T. A.
"Monoclonal antibody analysis of complex biological systems: Combination of cell hybridization and immunoadsorbents in a novel cascade procedure and its application to the macrophage cell surface."
J. Biol. Chem.  256: 3833-3839  (1981).    Pub#: 28  Endnote#: 2332

Ault, K. A., and Springer, T. A.
"Cross reaction of a rat-anti-mouse phagocyte-specific monoclonal antibody anti-Mac-1 with human monocytes and natural killer cells."
J. Immunol.  126: 359-364  (1981).    Pub#: 27  Endnote#: 784

Takei, F., Secher, D. S., Milstein, C., and Springer, T. A.
"Use of a monoclonal antibody specifically non-reactive with T cells to delineate lymphocyte subpopulations."
Immunology  42: 371-378  (1981).    Pub#: 26  Endnote#: 760

Springer, T. A.
"Mac-1,2,3, and 4: Murine macrophage differentiation antigens identified by monoclonal antibodies."
In Heterogeneity of mononuclear phagocytes, O. Förster and L. Mandy, eds. New York: Academic Press  37-46  (1981).    Pub#: 25  Endnote#: 0

Springer, T. A.
"Quantitation of light chain synthesis in myeloma x spleen cell hybrids and identification of myeloma chain loss variants using radioimmunoassay."
J. Immunol. Methods  37: 139-152  (1980).    Pub#: 24  Endnote#: 814

Springer, T. A.
"Cell-surface differentiation in the mouse. Characterization of "jumping" and "lineage" antigens using xenogeneic rat monoclonal antibodies."
In Monoclonal antibodies, R. H. Kennett, T. J. McKearn and K. B. Bechtol,eds. New York: Plenum Press  185-217  (1980).    Pub#: 23  Endnote#: 711

Springer, T. A., Galfre, G., Secher, D. S., and Milstein, C.
"Mac-1: a macrophage differentiation antigen identified by monoclonal antibody."
Eur.J.Immunol.  9: 301-306  (1979).    Pub#: 22  Endnote#: 535

Milstein, C., Galfre, G., Secher, D. S., and Springer, T. A.
"Monoclonal antibodies and cell surface antigens."
In Genetics and human biology: possibilities and realities.Ciba Foundation Symp.No.66 Amsterdam and reprinted in Cell. Biol. Internatl. Rep.: Excerpta Medica  1-16 and 251-266  (1979).    Pub#: 21  Endnote#: 2331

Springer, T. A., Galfre, G., Secher, D. S., and Milstein, C.
"Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens."
Eur.J.Immunol.  8: 539-551  (1978).    Pub#: 20  Endnote#: 534

Stern, P. L., Willison, K. R., Lennox, E., Galfre, G., Milstein, C., Secher, D., Ziegler, A., and Springer, T. A.
"Monoclonal antibodies as probes for differentiation and tumor-associated antigens: A Forssman specificity on teratocarcinoma stem cells."
Cell  14: 775-783  (1978).    Pub#: 19  Endnote#: 815

Springer, T. A., Galfre, G., Secher, D., and Milstein, C.
"Monoclonal xenogeneic antibodies to mouse leukocyte antigens: Identification of macrophage-specific and other differentiation antigens."
Curr. Topics Microbiol. Immunol.  81: 45-50  (1978).    Pub#: 18  Endnote#: 722

Springer, T. A., Kaufman, J., Terhorst, C., and Strominger, J. L.
"Studies of the structure of the human Ia-like antigen."
In Ir genes and Ia antigens, H. O. McDevit, ed. New York.: Academic Press  229-234  (1978).    Pub#: 17  Endnote#: 2440

Springer, T. A., Kaufman, J. F., Siddoway, L. A., Mann, D. L., and Strominger, J. L.
"Purification of HLA-linked B lymphocyte alloantigens in immunologically active form by preparative sodium dodecyl sulfate-gel electrophoresis and studies on their subunit association."
J. Biol. Chem.  252: 6201-6207  (1977).    Pub#: 16  Endnote#: 767

Springer, T. A., Kaufman, J. F., Terhorst, C., and Strominger, J. L.
"Purification and structural characterisation of human HLA-linked B-cell antigens."
Nature  268: 213-218  (1977).    Pub#: 15  Endnote#: 1054

Springer, T. A., Robb, R. J., Terhorst, C., and Strominger, J. L.
"Subunit and disulfide structure of monomeric and dimeric forms of detergent-soluble HLA antigens."
J. Biol. Chem.  252: 4694-4700  (1977).    Pub#: 14  Endnote#: 1055

Springer, T. A., Mann, D. L., DeFranco, A. L., and Strominger, J. L.
"Detergent solubilization, purification, and separation of specificities of HLA antigens from a cultured human lymphoblastoid line, RPMI 4265."
J. Biol. Chem.  252: 4682-4693  (1977).    Pub#: 13  Endnote#: 724

Springer, T. A., Kaufman, J. F., Siddoway, L. A., Giphart, M., Mann, D. L., Terhorst, C., and Strominger, J. L.
"Chemical and immunological characterization of HLA-linked B-lymphocyte alloantigens."
Cold Spring Harbor Symp. Quant. Biol.  41: 387-395  (1977).    Pub#: 12  Endnote#: 53

Springer, T. A., and Strominger, J. L.
"Detergent-soluble products of the HLA region."
Transplant. Proc.  9: 21-28  (1977).    Pub#: 11  Endnote#: 2438

Strominger, J. L., Mann, D. L., Parham, P., Robb, R., Springer, T. A., and Terhorst, C.
"Structure of HLA-A and HLA-B antigens isolated from cultured human lymphocytes."
Cold Spring Harbor Symp. Quant. Biol.  41: 323-329  (1977).    Pub#: 10  Endnote#: 2439

Strominger, J. L., Chess, L., Humphreys, R. E., Mann, D., Parham, P., Robb, R., Schlossman, S., Springer, T. A., and Terhorst, C.
"Isolation and structure of products of the human histocompatibility gene complex."
In Role of histocompatibility gene complex in immune responses. Proc. Int. Conf. at Brook Lodge, Mich., D. Katz and B. Benacerraf, eds. New York: Academic Press  621-643  (1976).    Pub#: 9  Endnote#: 2436

Springer, T. A., and Strominger, J. L.
"Detergent-soluble HLA antigens contain a hydrophilic region at the COOH-terminus and a penultimate hydrophobic region."
Proc. Natl. Acad. Sci. U.S.A.  73: 2481-2485  (1976).    Pub#: 8  Endnote#: 357

Strominger, J. L., Humphreys, R. E., Kaufman, J. F., Mann, D. L., Parham, P., Robb, R., Springer, T. A., and Terhorst, C.
"The structure of products of the major histocompatibility complex in man."
In 27. Mosbach Colloquium: The immune system, F. Melchers and K. Rajewsky, eds. Berlin: Springer-Verlag  202-219  (1976).    Pub#: 7  Endnote#: 2437

Strominger, J. L., Humphreys, R. E., McCune, J. M., Parham, P., Robb, R., Springer, T. A., and Terhorst, C.
"The immunoglobulin-like structure of human histocompatibility antigens."
Fed. Proc.  35: 1177-1182  (1976).    Pub#: 6  Endnote#: 2126

Strominger, J. L., Chess, L., Herrmann, H. C., Humphreys, R. E., Malenka, D., Mann, D., McCune, J. M., Parham, P., Robb, R., Springer, T. A., and Terhorst, C.
"Isolation of histocompatibility antigens and of several B-specific proteins from cultured human lymphocytes."
In Histocompatibility Testing, Kissmeyer-Nielsen, ed. Copenhagen: Munksgaard  719-730  (1975).    Pub#: 5  Endnote#: 1064

Strominger, J. L., Cresswell, P., Grey, H., Humphreys, R. E., Mann, D., McCune, J., Parham, P., Robb, R., Sanderson, A. R., Springer, T. A., Terhorst, C., and Turner, M. J.
"The immunoglobulin-like structure of human histocompatibility antigens."
Transplant. Rev.  21: 126-143  (1974).    Pub#: 4  Endnote#: 356

Cresswell, P., Springer, T. A., Strominger, J. L., Turner, M. J., Grey, H. M., and Kubo, R. T.
"Immunological identity of the small subunit of HL-A antigens and B2-microglobulin and its turnover on the cell membrane."
Proc. Natl. Acad. Sci. U.S.A.  71: 2123-2127  (1974).    Pub#: 3  Endnote#: 904

Springer, T. A., Strominger, J. L., and Mann, D.
"Partial purification of detergent solubilized HL-A antigen and its cleavage by papain."
Proc. Natl. Acad. Sci. U.S.A.  71: 1539-1543  (1974).    Pub#: 2  Endnote#: 1056

Grey, H. M., Kubo, R. T., Colon, S. M., Poulik, M. D., Cresswell, P., Springer, T. A., Turner, M., and Strominger, J. L.
"The small subunit of HL-A antigens is B2-microglobulin."
J. Exp. Med.  138: 1608-1612  (1973).    Pub#: 1  Endnote#: 928

Li-Zhi Mi, Michael J. Grey, Noritake Nishida, Thomas Walz, Chafen Lu, and Timothy A. Springer
"Functional and Structural Stability of the Epidermal Growth Factor Receptor in Detergent Micelles and Phospholipid Nanodiscs."
Biochemistry    (2008).    Pub#: 0  Endnote#: 18568
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